UNKL and DDX50

Number of citations of the paper that reports this interaction (PubMedID 34133714)
84

Data Source:
BioGRID (two hybrid)

		UNKL	DDX50
Description		unk like zinc finger	DExD-box helicase 50
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Nucleolus Cytoplasm Plasma Membrane Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity MRNA Binding Helicase Activity ATP Binding Hydrolase Activity ATP Hydrolysis Activity
	Biological Process	Protein Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Refractive error ( 32231278) Serum immune biomarker levels ( 32066700)
Interacting Genes		42 interacting genes: APOBEC3C ATXN1L BAG3 BAG4 CABP2 CARD9 CPSF2 CPSF7 CREB5 CRYBA2 CTBP1 DDX50 DMRTB1 EXOSC7 EXOSC8 FBLN1 FRS3 HNRNPF HOOK1 HOXA1 KCTD9 KDM1A KRT31 LMO1 MGAT5B NID2 NTAQ1 POLR1C PPP1R16A QKI RAB26 RAC1 RBPMS RNF10 RPS28 SAXO4 SMARCD2 SRPK2 TFIP11 TGM7 TRIM55 TRIM63	8 interacting genes: KRAS NXF1 PTEN PUF60 SRPK2 UBC UNKL USP7
Entrez ID		64718	79009
HPRD ID		15612	09910
Ensembl ID		ENSG00000059145	ENSG00000107625
Uniprot IDs		A0A0A0MRZ1 E9PDK2 Q9H9P5	Q9BQ39
PDB IDs			2E29
Enriched GO Terms of Interacting Partners?		RNA Binding U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing RNA Processing Transcription Coactivator Activity Nucleus RNA Metabolic Process MRNA Metabolic Process Negative Regulation Of Protein Targeting To Mitochondrion RNA 3'-end Processing Exoribonuclease Complex Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRAMP-dependent TRNA Surveillance Pathway TRNA Surveillance Nuclear Polyadenylation-dependent RRNA Catabolic Process Negative Regulation Of Establishment Of Protein Localization To Mitochondrion U4 SnRNA 3'-end Processing Identical Protein Binding RRNA 3'-end Processing Nucleolar Exosome (RNase Complex) TRNA Decay Nuclear MRNA Surveillance Ruffle Assembly Protein Binding Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity Adenyl-nucleotide Exchange Factor Activity MRNA Processing RRNA Catabolic Process Nuclear Exosome (RNase Complex) Exosome (RNase Complex) MRNA Cleavage And Polyadenylation Specificity Factor Complex Macromolecule Metabolic Process Positive Regulation Of Myelination Regulation Of RNA Splicing
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