ATF2 and CEBPG

Number of citations of the paper that reports this interaction (PMID 12805554)
98

Data Source:
BioGRID (fluorescent resonance energy transfer)
HPRD (in vitro)

		ATF2	CEBPG
Gene Name		activating transcription factor 2	CCAAT/enhancer binding protein (C/EBP), gamma
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrial Outer Membrane Site Of Double-strand Break	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Activating Transcription Factor Binding Enhancer Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding CAMP Response Element Binding Protein Binding Protein Kinase Binding CAMP Response Element Binding Metal Ion Binding Protein Heterodimerization Activity	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Double-stranded DNA Binding Protein Binding Transcription Factor Binding Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	Toll-like Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Outflow Tract Morphogenesis Chromatin Organization Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Response To Osmotic Stress Cellular Response To DNA Damage Stimulus Histone Acetylation Intra-S DNA Damage Checkpoint Positive Regulation Of Transforming Growth Factor Beta2 Production Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Toll-like Receptor 10 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Innate Immune Response Fat Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Stress-activated MAPK Cascade Adipose Tissue Development Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process	Liver Development Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Immune Response MRNA Metabolic Process B Cell Differentiation Natural Killer Cell Mediated Cytotoxicity Enucleate Erythrocyte Differentiation Positive Regulation Of DNA Binding Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Interferon-gamma Biosynthetic Process Positive Regulation Of DNA Repair Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Pathways		Organelle biogenesis and maintenance Toll Like Receptor 7/8 (TLR7/8) Cascade HATs acetylate histones Toll Like Receptor TLR6:TLR2 Cascade Activated TLR4 signalling Toll Like Receptor TLR1:TLR2 Cascade Activation of the AP-1 family of transcription factors MyD88 cascade initiated on plasma membrane Toll Like Receptor 5 (TLR5) Cascade MyD88 dependent cascade initiated on endosome TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation MyD88:Mal cascade initiated on plasma membrane Toll Like Receptor 9 (TLR9) Cascade Innate Immune System Chromatin organization TRIF-mediated TLR3/TLR4 signaling MAP kinase activation in TLR cascade MyD88-independent cascade Mitochondrial biogenesis Toll Like Receptor 2 (TLR2) Cascade Toll-Like Receptors Cascades Chromatin modifying enzymes Toll Like Receptor 10 (TLR10) Cascade Toll Like Receptor 3 (TLR3) Cascade Toll Like Receptor 4 (TLR4) Cascade MAPK targets/ Nuclear events mediated by MAP kinases Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		55 interactors: APP AR ATF3 ATF4 ATF7 BACH1 BATF BATF3 CCDC6 CCND1 CEBPA CEBPB CEBPG CREB5 CSNK2A1 CSNK2A2 DDIT3 EDF1 ETS1 EXOSC8 FOS FOSL1 GTF2F2 H2AFY HIST2H2BE HMGA1 IRF2BP1 JDP2 JUN KIFC3 MAPK1 MAPK10 MAPK11 MAPK13 MAPK14 MAPK8 MAPK9 MAPKAPK5 MLH1 NBN NCOA6 PML PRKCE RB1 RPS6KA5 RUVBL2 SMAD3 SMAD4 SRA1 SUMO1 THRB UBE2I UTF1 XPO1 YY1	22 interactors: ATF2 ATF3 ATF4 ATF5 BATF BATF2 BATF3 CEBPA CEBPB CEBPD CEBPE CREB3 CREB3L3 DBP DDIT3 FOS FOSL1 GTF2F2 JUN MLLT6 PLAU POLR2M
Entrez ID		1386	1054
HPRD ID		00443	00738
Ensembl ID		ENSG00000115966	ENSG00000153879
Uniprot IDs		A4D7V5 P15336	P53567
PDB IDs		1BHI 1T2K 4H36
Enriched GO Terms of Interacting Partners?		Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Gene Expression RNA Biosynthetic Process RNA Metabolic Process Gene Expression Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Metabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Biosynthetic Process Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Biosynthetic Process Positive Regulation Of Protein Metabolic Process Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of Cellular Protein Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Response To External Stimulus Negative Regulation Of Gene Expression Toll-like Receptor 3 Signaling Pathway	Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Gene Expression Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Cellular Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Response To Endoplasmic Reticulum Stress Positive Regulation Of Cellular Metabolic Process Response To External Stimulus Myeloid Leukocyte Differentiation Response To Biotic Stimulus Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Response To Stress Endoplasmic Reticulum Unfolded Protein Response Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Myeloid Cell Differentiation Response To Unfolded Protein Response To Other Organism Organ Development Cellular Response To Stress Leukocyte Differentiation Defense Response Myeloid Dendritic Cell Differentiation System Development Myeloid Dendritic Cell Activation Cellular Response To Organic Substance Response To Extracellular Stimulus Cellular Metabolic Process
Tagcloud ?		assayed atp compete competes diphosphorylated enzyme equal equally gly gst homogeneously ic50 inactive km monophosphorylated p38 preparations pyridinylimidazole pyridinylimidazoles s2 sb202190 sb203580 thr threonine transducing tritiated tyr ubiquitous unphosphorylated
Tagcloud (Difference) ?		assayed atp compete competes diphosphorylated enzyme equal equally gly gst homogeneously ic50 inactive km monophosphorylated p38 preparations pyridinylimidazole pyridinylimidazoles s2 sb202190 sb203580 thr threonine transducing tritiated tyr ubiquitous unphosphorylated
Tagcloud (Intersection) ?