NUP35 and NUP155

Number of citations of the paper that reports this interaction (PubMedID 35679425)
148

Data Source:
BioGRID (proximity labelling technology, pull down, affinity chromatography technology)

		NUP35	NUP155
Description		nucleoporin 35	nucleoporin 155
Image
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Plasma Membrane Membrane Nuclear Membrane Nuclear Pore Central Transport Channel Nuclear Pore Nuclear Basket	Nucleus Nuclear Envelope Nuclear Pore Cytosol Membrane Nuclear Membrane Nuclear Pore Inner Ring
	Molecular Function	Nucleic Acid Binding Protein Binding Phospholipid Binding Structural Constituent Of Nuclear Pore Identical Protein Binding	Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	NLS-bearing Protein Import Into Nucleus Nucleocytoplasmic Transport Nuclear Pore Organization Protein Transport MRNA Transport Cellular Response To Leukemia Inhibitory Factor	Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery RNA Export From Nucleus MRNA Export From Nucleus Protein Import Into Nucleus Nucleocytoplasmic Transport Nuclear Envelope Organization Protein Transport Protein Localization To Nucleus MiRNA Processing Protein Localization To Nuclear Inner Membrane MRNA Transport Atrial Cardiac Muscle Cell Action Potential
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation SARS-CoV-2 activates/modulates innate and adaptive immune responses	ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS		Bitter beverage consumption ( 31046077) Cerebral amyloid angiopathy x APOEe4 status interaction in Alzheimer’s disease ( 34020725) Metabolite levels ( 23823483) Platelet distribution width ( 32888494)	Malaria ( 31844061) Meat-related diet ( 32066663)
Interacting Genes		4 interacting genes: NUP155 NUP205 NUP93 PIN1	7 interacting genes: CDC42 EFS GLE1 NUP35 PDCD6IP UBC ZFYVE9
Entrez ID		129401	9631
HPRD ID		10486	05984
Ensembl ID		ENSG00000163002	ENSG00000113569
Uniprot IDs		Q8NFH5	B4DLT2 E9PF10 O75694
PDB IDs		4LIR 7MW1 7R5J 7R5K 8OZB	5A9Q 5IJN 5IJO 7EYE 7EYF 7EYQ 7PER 7R1Y 7R5J 7R5K
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Nuclear Pore Nuclear Pore Inner Ring Nuclear Pore RNA Transport MRNA Transport Nuclear Pore Complex Assembly Nuclear Pore Organization Nuclear Periphery Pore Complex Assembly Nucleobase-containing Compound Transport Nuclear Envelope Organization Nuclear Envelope Nuclear Transport Nucleocytoplasmic Transport Nuclear Membrane Establishment Of Protein Localization To Organelle Establishment Of Protein Localization MRNA Export From Nucleus Regulation Of SMAD Protein Signal Transduction RNA Export From Nucleus Nucleus Organization Cis-trans Isomerase Activity Protein Import Into Nucleus Import Into Nucleus Nuclear Export Protein Peptidyl-prolyl Isomerization Phosphothreonine Residue Binding Protein Localization To Nuclear Inner Membrane Dendritic Microtubule Protein Localization To Nucleus Positive Regulation Of Dendritic Spine Maintenance Phosphoserine Residue Binding Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Organelle Organization Protein Transport Atrial Cardiac Muscle Cell Action Potential Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Mitogen-activated Protein Kinase Kinase Binding Intracellular Transport GTPase Activating Protein Binding Ubiquitin Ligase Activator Activity Protein-containing Complex Assembly Regulation Of Dendritic Spine Maintenance Protein Localization To Nuclear Envelope Protein-containing Complex Organization Microtubule Polymerization Cellular Localization Establishment Of Localization In Cell Poly(A)+ MRNA Export From Nucleus Nucleus	Apolipoprotein A-I Receptor Binding Cellular Localization Endothelin Receptor Signaling Pathway Involved In Heart Process Focal Adhesion Establishment Or Maintenance Of Apical/basal Cell Polarity Centrosome Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Neuropilin Signaling Pathway GBD Domain Binding Storage Vacuole Establishment Of Localization In Cell Intracellular Transport Establishment Or Maintenance Of Cell Polarity RNA Transport Inositol Hexakisphosphate Binding Nuclear Pore Cytoplasmic Filaments Phospholipid Binding MRNA Transport Nuclear Pore Extracellular Vesicle Biogenesis Extracellular Exosome Biogenesis Nucleus Organization Positive Regulation Of Extracellular Exosome Assembly Proteinase Activated Receptor Binding Actomyosin Contractile Ring Assembly Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cell-cell Junction Organization Positive Regulation Of Pinocytosis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Extracellular Exosome Assembly Nuclear Pore Central Transport Channel Intracellular Protein Localization Nucleobase-containing Compound Transport Nuclear Envelope Establishment Of Golgi Localization Protein Domain Specific Binding Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Leading Edge Membrane Thioesterase Binding Neuron Fate Determination Golgi Transport Complex Actomyosin Nuclear Transport Nucleocytoplasmic Transport Endothelin Receptor Signaling Pathway Cell Junction Assembly Cytosol
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