SGSM1 and CETN1

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		SGSM1	CETN1
Description		small G protein signaling modulator 1	centrin 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle	Spindle Pole Nucleus Cytoplasm Centrosome Centriole Microtubule Organizing Center Cytosol Cytoskeleton Cilium Photoreceptor Connecting Cilium Cell Projection
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Binding Metal Ion Binding
	Biological Process		Microtubule Cytoskeleton Organization Centriole Replication Cellular Response To Heat Cell Division
Pathways			Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Insulin-related traits (multivariate analysis) ( 32002517) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Night sleep phenotypes ( 27126917) Primary sclerosing cholangitis ( 27992413) Refractive astigmatism ( 30306274) Resting-state electroencephalogram vigilance ( 29703947)
Interacting Genes		1 interacting genes: CETN1	4 interacting genes: CCP110 POC5 PRKACA SGSM1
Entrez ID		129049	1068
HPRD ID		18969	04425
Ensembl ID		ENSG00000167037	ENSG00000177143
Uniprot IDs		A0A087X241 Q2NKQ1	A0A140VJG3 Q12798
PDB IDs
Enriched GO Terms of Interacting Partners?		Heterotrimeric G-protein Binding Centriole Assembly Centriole Replication G-protein Beta/gamma-subunit Complex Binding Cellular Response To Heat Photoreceptor Connecting Cilium Microtubule Organizing Center Organization Microtubule Organizing Center Response To Heat Centriole Response To Temperature Stimulus Spindle Pole Microtubule Binding Membraneless Organelle Assembly	CAMP-dependent Protein Kinase Complex Protein-lipid Complex Assembly Protein Serine/threonine/tyrosine Kinase Activity Regulation Of Cardiac Conduction Vascular Endothelial Cell Response To Fluid Shear Stress Cellular Response To Parathyroid Hormone Stimulus Negative Regulation Of Glycolytic Process Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Cellular Response To Glucagon Stimulus Centrosome Negative Regulation Of Interleukin-2 Production Response To Laminar Fluid Shear Stress Sperm Capacitation CAMP-dependent Protein Kinase Activity Interleukin-2-mediated Signaling Pathway Calcium Channel Complex Cellular Response To Laminar Fluid Shear Stress Negative Regulation Of ATP Metabolic Process Plasma Lipoprotein Particle Assembly Regulation Of Bicellular Tight Junction Assembly Cellular Response To Epinephrine Stimulus Multicellular Organismal-level Water Homeostasis Positive Regulation Of Cholesterol Biosynthetic Process Cell Communication By Electrical Coupling High-density Lipoprotein Particle Assembly Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Renal Water Homeostasis Response To Parathyroid Hormone Positive Regulation Of Gluconeogenesis Response To Glucagon Positive Regulation Of Protein Export From Nucleus Cellular Response To Cold Cell Communication By Electrical Coupling Involved In Cardiac Conduction Protein Localization To Lipid Droplet Cilium Intracellular Potassium Ion Homeostasis Protein Kinase A Regulatory Subunit Binding Mitochondrial Protein Catabolic Process Response To Epinephrine CAMP/PKA Signal Transduction Nucleotide-activated Protein Kinase Complex Channel Activator Activity Cell Communication Involved In Cardiac Conduction Regulation Of Cell Cycle Vascular Endothelial Cell Response To Laminar Fluid Shear Stress Negative Regulation Of Cilium Assembly Centriole Centriole Replication Centrosome Duplication Ciliary Basal Body Organization
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