VSTM2L and WIPF3

Number of citations of the paper that reports this interaction (PubMedID 11553796)
22

Data Source:
HPRD (in vitro, in vivo)

		VSTM2L	WIPF3
Description		V-set and transmembrane domain containing 2 like	WAS/WASL interacting protein family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Membrane	Cytoplasm Early Endosome Cytosol Recycling Endosome WASH Complex
	Molecular Function	Protein Binding	Actin Binding Protein Binding Alpha-tubulin Binding Gamma-tubulin Binding
	Biological Process	Negative Regulation Of Neuron Apoptotic Process	Exocytosis Spermatogenesis Cell Differentiation Endocytic Recycling Arp2/3 Complex-mediated Actin Nucleation Retrograde Transport, Endosome To Golgi
Pathways			Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs CDC42 GTPase cycle RAC1 GTPase cycle FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Levodopa wearing off effect (time symptoms uncontrolled) in Parkinson's disease (response to zonisamide) ( 32355309)	Corneal curvature ( 22969067) Facial emotion recognition ( 28608620) Facial emotion recognition (angry faces) ( 28608620) Facial emotion recognition (sad faces) ( 28608620) Heel bone mineral density ( 30598549) Microalbuminuria ( 31511532) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31511532 31630189)
Interacting Genes		3 interacting genes: ATXN1 SRPK2 WIPF3	2 interacting genes: VSTM2L WASL
Entrez ID		128434	644150
HPRD ID		12735	18947
Ensembl ID		ENSG00000132821	ENSG00000122574
Uniprot IDs		Q96N03	A0A0A0MSG0 A6NGB9
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Membrane Tubulation Positive Regulation Of Clathrin-dependent Endocytosis Actin Cap Vesicle Transport Along Actin Filament Negative Regulation Of Lymphocyte Migration Regulation Of Plasma Membrane Organization Dendritic Spine Morphogenesis Regulation Of Clathrin-dependent Endocytosis Actin Filament Polymerization GTPase Regulator Activity Vesicle Budding From Membrane Positive Regulation Of Filopodium Assembly Dendritic Spine Organization Negative Regulation Of Mononuclear Cell Migration Neuron Projection Organization Regulation Of Filopodium Assembly Postsynapse Organization Vesicle Cytoskeletal Trafficking Negative Regulation Of Leukocyte Migration Actin Polymerization Or Depolymerization Positive Regulation Of Receptor-mediated Endocytosis Spindle Localization Actin Filament-based Movement Regulation Of Lymphocyte Migration Protein-containing Complex Localization Endocytic Vesicle Membrane Protein Polymerization
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