TMIGD2 and ACER1

		TMIGD2	ACER1
Description		transmembrane and immunoglobulin domain containing 2	alkaline ceramidase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Neuron Projection	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Coreceptor Activity	Protein Binding Hydrolase Activity Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides N-acylsphingosine Amidohydrolase Activity Metal Ion Binding
	Biological Process	Positive Regulation Of Cytokine Production T Cell Costimulation Positive Regulation Of Activated T Cell Proliferation Positive Regulation Of Angiogenesis	Lipid Metabolic Process Sphingolipid Metabolic Process Ceramide Metabolic Process Epidermis Development Response To Alkaline PH Regulation Of Lipid Metabolic Process Sphingolipid Biosynthetic Process Sphingolipid Catabolic Process Cell Differentiation Keratinocyte Differentiation Sphingosine Biosynthetic Process Ceramide Catabolic Process Sebaceous Gland Development Cellular Response To Calcium Ion
Pathways			Sphingolipid catabolism
Drugs
Diseases
GWAS		Post-bronchodilator lung function in asthma (FVC) ( 32989782)	Diffusing capacity of carbon monoxide ( 30694715)
Interacting Genes			1 interacting genes: MPP1
Entrez ID		126259	125981
HPRD ID		14487	12496
Ensembl ID		ENSG00000167664	ENSG00000167769
Uniprot IDs		A0A0B4J2A9 Q96BF3	Q8TDN7
PDB IDs
Enriched GO Terms of Interacting Partners?		Sphingosine Biosynthetic Process Response To Alkaline PH Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides N-acylsphingosine Amidohydrolase Activity Sebaceous Gland Development Sphingoid Biosynthetic Process MICOS Complex Mitochondrial Crista Junction SAM Complex Cristae Formation MIB Complex Sphingosine Metabolic Process Ceramide Catabolic Process Diol Metabolic Process	GMP Kinase Activity GDP Metabolic Process Stereocilium Regulation Of Neutrophil Chemotaxis Cortical Cytoskeleton GMP Metabolic Process Regulation Of Neutrophil Migration Positive Regulation Of Activated T Cell Proliferation T Cell Costimulation Regulation Of Activated T Cell Proliferation Regulation Of Granulocyte Chemotaxis
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