TMEM219 and SGF29

		TMEM219	SGF29
Description		transmembrane protein 219	SAGA complex associated factor 29
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	SAGA Complex Nucleus Nucleoplasm SAGA-type Complex Mitotic Spindle ATAC Complex
	Molecular Function	Protein Binding	Protein Binding Histone H3K4me3 Reader Activity Histone H3K36me3 Reader Activity Methylation-dependent Protein Binding
	Biological Process	Apoptotic Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA Repair Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Response To Endoplasmic Reticulum Stress Regulation Of RNA Splicing Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development Regulation Of Cell Division Regulation Of Cell Cycle Regulation Of Macromolecule Metabolic Process Establishment Of Protein Localization To Chromatin
Pathways		TP53 Regulates Transcription of Death Receptors and Ligands	HATs acetylate histones Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety/tension (special factor of neuroticism) ( 30867560) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Schizophrenia ( 25056061 28991256 29483656) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes			26 interacting genes: C20orf202 CCDC102B CCDC158 CLHC1 DBF4B H3-4 KRT13 KRT15 KRT16 KRT19 KRT24 KRT33B LNX1 LZTS1 MED11 MED4 MYF5 PROSER3 RINT1 SYCE3 SYNPO TADA3 TCF4 TEX12 TFIP11 TRAF3IP1
Entrez ID		124446	112869
HPRD ID		18546	13996
Ensembl ID		ENSG00000149932	ENSG00000176476
Uniprot IDs		A0A024R618 Q86XT9	Q96ES7
PDB IDs			3LX7 3ME9 3MEA 3MET 3MEU 3MEV 3MEW 5C0M
Enriched GO Terms of Interacting Partners?		Vesicle Fusion To Plasma Membrane Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Synaptic Vesicle Membrane Organization Negative Regulation Of Short-term Synaptic Potentiation Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Negative Regulation Of Synaptic Vesicle Recycling Vesicle Fusion Negative Regulation Of SNARE Complex Assembly Postsynaptic Density Membrane Organelle Membrane Fusion Regulation Of Calcium-dependent Activation Of Synaptic Vesicle Fusion Methylation-dependent Protein Binding Modulation Of Chemical Synaptic Transmission Negative Regulation Of Vesicle Fusion Organelle Fusion Regulation Of Synaptic Activity Regulation Of Vesicle-mediated Transport Negative Regulation Of Pinocytosis Membrane Fusion Regulation Of Spontaneous Synaptic Transmission Spontaneous Neurotransmitter Secretion SAGA-type Complex Histone H3K36me3 Reader Activity Regulation Of Synaptic Plasticity Calcium Ion-regulated Exocytosis Of Neurotransmitter Establishment Of Protein Localization To Chromatin Neuromuscular Process Controlling Posture Presynapse Nuclear Lamina Synaptic Vesicle Docking Regulation Of Synaptic Vesicle Priming Asymmetric Synapse ATAC Complex Regulation Of Short-term Neuronal Synaptic Plasticity Regulation Of SNARE Complex Assembly	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Tissue Morphogenesis Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Cytoskeleton Central Element Supramolecular Fiber Organization Hair Cycle Protein-DNA Complex Assembly Synaptonemal Complex Assembly Structural Constituent Of Cytoskeleton Synaptonemal Complex Organization Core Mediator Complex Organelle Organization Anatomical Structure Morphogenesis Protein Binding Spine Apparatus Assembly Mediator Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?