TRAPPC6B and TRAPPC3L

Number of citations of the paper that reports this interaction (PubMedID 21525244)
43

Data Source:
BioGRID (two hybrid, two hybrid)

		TRAPPC6B	TRAPPC3L
Description		trafficking protein particle complex subunit 6B	trafficking protein particle complex subunit 3L
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex TRAPPII Protein Complex	Endoplasmic Reticulum Golgi Apparatus Cytosol TRAPP Complex Cis-Golgi Network Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Coating Nervous System Development Golgi Vesicle Transport Vesicle Tethering	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Golgi Vesicle Transport
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs		S-palmitoyl-L-cysteine
Diseases
GWAS			Refractive error ( 32231278) Ulcerative colitis ( 28067908)
Interacting Genes		6 interacting genes: SNCA TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC3L TRAPPC6A	12 interacting genes: TRAPPC1 TRAPPC10 TRAPPC11 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC4 TRAPPC5 TRAPPC6A TRAPPC6B TRAPPC8 TRAPPC9
Entrez ID		122553	100128327
HPRD ID		18221	19437
Ensembl ID		ENSG00000182400	ENSG00000173626
Uniprot IDs		Q86SZ2	Q5T215
PDB IDs		2BJN 2CFH 3KXC
Enriched GO Terms of Interacting Partners?		TRAPP Complex Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Tethering Vesicle Coating TRAPPIII Protein Complex Golgi Vesicle Transport COPII Vesicle Coating Vesicle-mediated Transport Establishment Of Localization In Cell Vesicle Organization TRAPPII Protein Complex Intracellular Transport Cellular Localization Intra-Golgi Vesicle-mediated Transport Organelle Organization Endoplasmic Reticulum-Golgi Intermediate Compartment Protein-containing Complex Assembly Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Golgi Apparatus Protein-containing Complex Organization Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Protein Localization To Kinetochore Cytosol Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Regulation Of Kinetochore Assembly Perinuclear Region Of Cytoplasm Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process Dopamine Uptake Involved In Synaptic Transmission Regulation Of Centromere Complex Assembly Response To Iron(II) Ion Regulation Of Chaperone-mediated Autophagy Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Oxidative Phosphorylation Mitochondrial ATP Synthesis Coupled Electron Transport Cuprous Ion Binding Dopamine Biosynthetic Process Negative Regulation Of Cellular Respiration Regulation Of Acyl-CoA Biosynthetic Process Supramolecular Fiber	TRAPP Complex Vesicle Tethering Vesicle Coating TRAPPIII Protein Complex Endoplasmic Reticulum To Golgi Vesicle-mediated Transport COPII Vesicle Coating TRAPPII Protein Complex Golgi Vesicle Transport Vesicle Organization Vesicle-mediated Transport Intracellular Transport Cellular Localization Establishment Of Localization In Cell Golgi Apparatus Organelle Organization Protein-containing Complex Assembly Protein-containing Complex Organization Cytosol Endoplasmic Reticulum Cellular Component Assembly Cytoplasm Golgi Organization Trans-Golgi Network Cis-Golgi Network TRAPPI Protein Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Positive Regulation Of Protein Localization To Kinetochore Regulation Of Kinetochore Assembly Regulation Of Centromere Complex Assembly Constitutive Secretory Pathway Collagen Biosynthetic Process Perinuclear Region Of Cytoplasm Regulation Of Protein Complex Stability Early Endosome To Golgi Transport
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