TRAPPC6B

Description		trafficking protein particle complex subunit 6B
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cis-Golgi Network Trans-Golgi Network Cytosol TRAPP Complex TRAPPII Protein Complex
	Molecular Function	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Coating Nervous System Development Golgi Vesicle Transport Vesicle Tethering
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs		S-palmitoyl-L-cysteine
Diseases
GWAS
Interacting Genes		6 interacting genes: SNCA TRAPPC10 TRAPPC12 TRAPPC2 TRAPPC3L TRAPPC6A
Entrez ID		122553
HPRD ID		18221
Ensembl ID		ENSG00000182400
Uniprot IDs		Q86SZ2
PDB IDs		2BJN 2CFH 3KXC
Enriched GO Terms of Interacting Partners?		TRAPP Complex Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Tethering Vesicle Coating TRAPPIII Protein Complex Golgi Vesicle Transport COPII Vesicle Coating Vesicle-mediated Transport Establishment Of Localization In Cell Vesicle Organization TRAPPII Protein Complex Intracellular Transport Cellular Localization Intra-Golgi Vesicle-mediated Transport Organelle Organization Endoplasmic Reticulum-Golgi Intermediate Compartment Protein-containing Complex Assembly Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Golgi Apparatus Protein-containing Complex Organization Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Protein Localization To Kinetochore Cytosol Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Regulation Of Kinetochore Assembly Perinuclear Region Of Cytoplasm Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process Dopamine Uptake Involved In Synaptic Transmission Regulation Of Centromere Complex Assembly Response To Iron(II) Ion Regulation Of Chaperone-mediated Autophagy Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Oxidative Phosphorylation Mitochondrial ATP Synthesis Coupled Electron Transport Cuprous Ion Binding Dopamine Biosynthetic Process Negative Regulation Of Cellular Respiration Regulation Of Acyl-CoA Biosynthetic Process Supramolecular Fiber
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