ASCL4 and PDZD4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ASCL4	PDZD4
Description		achaete-scute family bHLH transcription factor 4	PDZ domain containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex RNA Polymerase II Transcription Regulator Complex	Cytoplasm Cell Cortex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Skin Development Animal Organ Development Epithelium Development
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Daytime nap ( 33568662) Pelvic organ prolapse (moderate/severe) ( 26545240) Sleep duration ( 30846698)
Interacting Genes		6 interacting genes: CRK FHL3 MBD3 PDZD4 TCF12 TCF4	15 interacting genes: APIP APP ASCL4 CEP76 CTDSP1 DNMT3L DYDC1 ENKD1 GFI1B IKZF3 JRK KCTD9 MTUS2 TRAF2 TRAF3
Entrez ID		121549	57595
HPRD ID		12374	06601
Ensembl ID		ENSG00000187855	ENSG00000067840
Uniprot IDs		Q6XD76	B3KW03 Q17RL8 Q76G19
PDB IDs
Enriched GO Terms of Interacting Partners?		Helper T Cell Diapedesis Cerebellar Neuron Development Protein Phosphorylated Amino Acid Binding Response To Cholecystokinin Muscle Organ Development Muscle Structure Development Positive Regulation Of Neuron Differentiation Beta-catenin-TCF7L2 Complex E-box Binding TFIIB-class Transcription Factor Binding Protein Dimerization Activity Regulation Of Neuron Differentiation	Thioesterase Binding CD40 Receptor Complex
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