ARL14EP and SETDB2

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology)

		ARL14EP	SETDB2
Description		ARF like GTPase 14 effector protein	SET domain bifurcated histone lysine methyltransferase 2
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol
	Molecular Function	Protein Binding	DNA Binding Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone Methyltransferase Activity Metal Ion Binding Histone H3K9 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone H3K9 Monomethyltransferase Activity
	Biological Process		Mitotic Cell Cycle Heart Looping Chromatin Organization Chromatin Remodeling Chromosome Segregation Negative Regulation Of Gene Expression Methylation Negative Regulation Of DNA-templated Transcription Cell Division Heterochromatin Organization Left/right Axis Specification
Pathways			PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first birth ( 34211149) Chronotype ( 30696823) Heel bone mineral density ( 30598549) Morning person ( 30696823) Polycystic ovary syndrome ( 26284813 30566500) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure ( 30224653)	Mean spheric corpuscular volume ( 32888494) Refractive error ( 32231278)
Interacting Genes		3 interacting genes: KANK2 PLEKHF2 SETDB2	1 interacting genes: ARL14EP
Entrez ID		120534	83852
HPRD ID		08796	09712
Ensembl ID		ENSG00000152219	ENSG00000136169
Uniprot IDs		Q8N8R7	Q96T68
PDB IDs		8HFP	5TFP 8HFP
Enriched GO Terms of Interacting Partners?		BLOC-2 Complex Negative Regulation Of Vitamin D Receptor Signaling Pathway
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