TLCD1 and TMEM80

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TLCD1	TMEM80
Description		TLC domain containing 1	transmembrane protein 80
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Cilium Membrane Ciliary Transition Zone Cell Projection
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Plasma Membrane Organization Phospholipid Homeostasis Membrane Assembly Regulation Of Membrane Lipid Distribution	Non-motile Cilium Assembly
Pathways
Drugs
Diseases
GWAS
Interacting Genes		8 interacting genes: AQP6 CD40 CREB3L1 EBP FXYD3 SSMEM1 TMEM14B TMEM80	65 interacting genes: ADGRE2 AGTR1 AIG1 AQP1 ARL6IP6 BET1 BIK C11orf24 C14orf180 C3orf52 C5orf46 CCDC167 CD63 CLDN11 CLDN19 CLDN8 CLDND2 CLEC2D CMTM5 CNIH3 COL4A5 CXCR2 CYBC1 DOLK EMD ERMP1 FAM20B FAM3C FKBP8 FXYD3 GPR37L1 IER3IP1 LAT LSMEM1 MALL MRAP2 NKG7 PRB1 PTPN9 PTPRN RPRM SERP2 SLC30A8 SLC66A2 SMAGP SMCO4 STATH STX7 SYNGR1 TLCD1 TMEM100 TMEM107 TMEM109 TMEM120B TMEM128 TMEM14A TMEM243 TMEM65 TNFRSF10C TRARG1 TSPAN1 TSPO2 TVP23B VKORC1L1 WNT4
Entrez ID		116238	283232
HPRD ID		14015	14143
Ensembl ID		ENSG00000160606	ENSG00000177042
Uniprot IDs		Q96CP7	A0A0A0MTU4 A0AAA9X375 E9PQJ9 Q96HE8
PDB IDs
Enriched GO Terms of Interacting Partners?		PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Chloride Transmembrane Transport Inorganic Anion Transmembrane Transport Chloride Transport Membrane Positive Regulation Of Interleukin-4-mediated Signaling Pathway Positive Regulation Of Protein Kinase C Signaling Response To Cobalamin Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol C-8 Sterol Isomerase Activity Cholesterol-5,6-oxide Hydrolase Activity Steroid Delta-isomerase Activity Cholestenol Delta-isomerase Activity Extracellular Matrix Constituent Secretion Monoatomic Anion Transmembrane Transport Inorganic Anion Transport Monoatomic Anion Transport Cellular Response To Erythropoietin Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Regulation Of Protein Kinase C Signaling Response To Erythropoietin	Membrane Plasma Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Protein Binding
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