TENT5B and ACY1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TENT5B	ACY1
Description		terminal nucleotidyltransferase 5B	aminoacylase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Transferase Activity Nucleotidyltransferase Activity Poly(A) RNA Polymerase Activity	Aminoacylase Activity Protein Binding Hydrolase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Apoptotic Process Positive Regulation Of Translation Negative Regulation Of Cell Cycle MRNA Stabilization	Amino Acid Metabolic Process
Pathways			Aflatoxin activation and detoxification Defective ACY1 causes encephalopathy Paracetamol ADME
Drugs			Aspartic acid Acetylcysteine Copper
Diseases
GWAS			Serum metabolite concentrations in chronic kidney disease ( 33838163)
Interacting Genes		61 interacting genes: ACY1 AKAP8L AKAP9 ATXN1 BHLHE40 C10orf55 C3orf36 CERCAM CIMIP2B CYSRT1 DAZAP2 ENKD1 FAM168B FOS FOSB FOXI1 HIVEP1 HMGXB4 HNRNPF KLHL38 KRT34 KRTAP19-6 KRTAP6-1 KRTAP6-2 MGAT5B MKRN3 NAF1 NICN1 NR1D2 OTX2 PLK4 POU2AF1 POU6F2 PROP1 PSMB8 PSMF1 RBPMS2 RFX6 RHOXF2 RIMBP3C RUSC1 SLC15A2 SLC27A4 SMAP2 SOHLH1 SOX5 SPAG8 TBX6 TENT5A TLE5 TNS2 TRIP13 UBAP2 UBQLN2 USP54 YPEL3 ZBTB2 ZC3H10 ZNF503 ZNF620 ZNF688	11 interacting genes: APP BCAS2 NPM1 NTAQ1 POT1 PRR35 TENT5B TERF1 TLX3 TTC1 WWOX
Entrez ID		115572	95
HPRD ID		16882	00092
Ensembl ID		ENSG00000158246	ENSG00000243989
Uniprot IDs		Q96A09	Q03154 V9HWA0
PDB IDs			1Q7L
Enriched GO Terms of Interacting Partners?		Identical Protein Binding DNA-binding Transcription Factor Activity DNA Binding Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of RNA Metabolic Process Nucleus Chromatin RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process	Shelterin Complex Nuclear Telomere Cap Complex Telomeric D-loop Disassembly G-rich Strand Telomeric DNA Binding Telomeric Loop Disassembly Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Telomeric DNA Binding Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of MRNA Stability Involved In Cellular Response To UV Regulation Of EIF2 Alpha Phosphorylation By DsRNA Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Protein-N-terminal Glutamine Amidohydrolase Activity Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Negative Regulation Of Cell Cycle Regulation Of Endoribonuclease Activity Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of Telomeric Loop Disassembly Protein-N-terminal Asparagine Amidohydrolase Activity Regulation Of DNA Biosynthetic Process DNA Biosynthetic Process PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?