BUD23 and DNAAF5

		BUD23	DNAAF5
Description		BUD23 rRNA methyltransferase and ribosome maturation factor	dynein axonemal assembly factor 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Perinuclear Region Of Cytoplasm	Nucleolus Cytoplasm Cytosol Microtubule Cytoskeleton Motile Cilium Mitotic Spindle Dynein Axonemal Particle
	Molecular Function	RNA Binding Protein Binding Methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity RRNA (guanine) Methyltransferase Activity Transferase Activity Protein Heterodimerization Activity	Dynein Intermediate Chain Binding
	Biological Process	Chromatin Organization RRNA Processing Methylation Ribosome Biogenesis RRNA (guanine-N7)-methylation Positive Regulation Of RRNA Processing	Cilium Movement Cell Projection Organization Outer Dynein Arm Assembly Inner Dynein Arm Assembly
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Cerebrospinal P-tau181p levels ( 28247064) Initial pursuit acceleration ( 29064472) Retinitis pigmentosa ( 33514863)
Interacting Genes		6 interacting genes: CEBPA DNMT3B OAS1 PKN1 UBC VCP	5 interacting genes: FEZ1 PFKL USP39 WEE2-AS1 ZBTB16
Entrez ID		114049	54919
HPRD ID		15659	07903
Ensembl ID		ENSG00000071462	ENSG00000164818
Uniprot IDs		O43709	B3KPE2 Q86Y56
PDB IDs		6G4W 7WTS 7WTT 7WTU 7WTV 7WTW
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Respiration Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nucleoplasm Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Immune System Process CHOP-C/EBP Complex Histone Deacetylase Binding Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Response To Vitamin B2 Multicellular Organismal-level Homeostasis C/EBP Complex Positive Regulation Of Proteasomal Protein Catabolic Process DNA (cytosine-5-)-methyltransferase Activity, Acting On CpG Substrates DNA-methyltransferase Activity DNA (cytosine-5-)-methyltransferase Activity Regulation Of Cellular Respiration Regulation Of Generation Of Precursor Metabolites And Energy Histone H3T11 Kinase Activity Flavin Adenine Dinucleotide Catabolic Process VCP-NSFL1C Complex Cellular Response To Arsenite Ion Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Mitotic Spindle Disassembly Positive Regulation Of Oxidative Phosphorylation Positive Regulation Of Protein K63-linked Deubiquitination Positive Regulation Of Biosynthetic Process White Fat Cell Proliferation Negative Regulation Of IP-10 Production Negative Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production 2'-5'-oligoadenylate Synthetase Activity Cytoplasm Protein Quality Control BAT3 Complex Binding Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Regulation Of Ribonuclease Activity Positive Regulation Of Protein Deubiquitination Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Macromolecule Metabolic Process Carbohydrate Homeostasis Response To Phenylpropanoid Glucose Homeostasis Regulation Of Proteasomal Protein Catabolic Process Protein-containing Complex Intracellular Signal Transduction Positive Regulation Of Protein Catabolic Process Fat Cell Proliferation Interleukin-27-mediated Signaling Pathway
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