RPUSD1 and FOXJ1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		RPUSD1	FOXJ1
Description		RNA pseudouridine synthase domain containing 1	forkhead box J1
Image			No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus
	Molecular Function	RNA Binding Protein Binding Pseudouridine Synthase Activity	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Enzyme-directed RRNA Pseudouridine Synthesis Pseudouridine Synthesis RNA Modification	Negative Regulation Of Transcription By RNA Polymerase II Central Tolerance Induction Negative Regulation Of Germinal Center Formation Positive Regulation Of Central B Cell Tolerance Induction Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Humoral Immune Response Spermatogenesis Determination Of Left/right Symmetry Pattern Specification Process Brain Development Heart Development Intracellular Protein Localization Cell Projection Organization Actin Cytoskeleton Organization Regulation Of Epithelial Cell Differentiation Ciliary Basal Body Organization Negative Regulation Of Interleukin-6 Production Negative Regulation Of T Cell Differentiation In Thymus Axoneme Assembly Establishment Of Apical/basal Cell Polarity Metanephric Part Of Ureteric Bud Development Negative Regulation Of T Cell Proliferation Motile Cilium Assembly Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Cell Maturation Negative Regulation Of B Cell Activation Leukocyte Migration Cilium Assembly Lung Epithelium Development Epithelium Development Left/right Pattern Formation Glomerular Parietal Epithelial Cell Development Negative Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Lung Ciliated Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971)
Interacting Genes		1 interacting genes: FOXJ1	8 interacting genes: NMRAL1 OIP5 RFX2 RPUSD1 SLC37A3 THRA TRMT6 TWF2
Entrez ID		113000	2302
HPRD ID		08507	03798
Ensembl ID		ENSG00000007376	ENSG00000129654
Uniprot IDs		H3BQN8 H3BUN6 Q9UJJ7	Q92949
PDB IDs		5VBB
Enriched GO Terms of Interacting Partners?		Glomerular Parietal Epithelial Cell Development Positive Regulation Of Central B Cell Tolerance Induction Central Tolerance Induction Positive Regulation Of Lung Ciliated Cell Differentiation Positive Regulation Of B Cell Tolerance Induction Negative Regulation Of Germinal Center Formation Metanephric Part Of Ureteric Bud Development Ciliary Basal Body Organization Regulation Of Germinal Center Formation Negative Regulation Of T Cell Differentiation In Thymus Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Tolerance Induction Lung Epithelium Development Left/right Pattern Formation Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Tolerance Induction Regulation Of Tolerance Induction Establishment Of Apical/basal Cell Polarity Establishment Of Monopolar Cell Polarity Regulation Of T Cell Differentiation In Thymus Establishment Or Maintenance Of Monopolar Cell Polarity Negative Regulation Of Non-canonical NF-kappaB Signal Transduction Negative Regulation Of B Cell Activation Negative Regulation Of Interleukin-6 Production Establishment Or Maintenance Of Apical/basal Cell Polarity Regulation Of Humoral Immune Response Motile Cilium Assembly Axoneme Assembly Negative Regulation Of T Cell Differentiation Negative Regulation Of Lymphocyte Differentiation Positive Regulation Of Epithelial Cell Differentiation Negative Regulation Of Adaptive Immune Response Negative Regulation Of T Cell Proliferation Negative Regulation Of Lymphocyte Proliferation Determination Of Bilateral Symmetry Negative Regulation Of Mononuclear Cell Proliferation Microtubule Organizing Center Organization Establishment Of Cell Polarity Determination Of Left/right Symmetry Microtubule Bundle Formation Negative Regulation Of Leukocyte Proliferation Regulation Of Non-canonical NF-kappaB Signal Transduction Negative Regulation Of Hemopoiesis Epithelial Cell Development Regulation Of B Cell Activation Negative Regulation Of T Cell Activation Negative Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Epithelial Cell Differentiation Cell Maturation Establishment Or Maintenance Of Cell Polarity
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