PRR4 and MIEF1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PRR4	MIEF1
Description		proline rich 4	mitochondrial elongation factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Mitochondrion Mitochondrial Outer Membrane Peroxisome Membrane
	Molecular Function	Protein Binding	Nucleotide Binding Protein Binding GDP Binding Identical Protein Binding ADP Binding
	Biological Process	Visual Perception	Mitochondrial Fission Mitochondrion Organization Mitochondrial Fusion Positive Regulation Of Mitochondrial Fusion Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Targeting To Membrane
Pathways			Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		Caffeine consumption from tea ( 33287642)	Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular hemoglobin ( 32888494)
Interacting Genes		6 interacting genes: GET3 LAT MIEF1 SGTB UBQLN1 UBQLN2	22 interacting genes: ABHD5 AGTRAP ARFIP2 ATP5PF CMTM5 CMTM6 DNM1L FAM25A FAM25C FAM25G HTATIP2 MAGEA1 MED21 PLIN3 PRAF2 PRR4 PSMA1 SYP TNFRSF10D UBQLN1 UBQLN2 YWHAG
Entrez ID		11272	54471
HPRD ID		09248	13371
Ensembl ID		ENSG00000111215	ENSG00000100335
Uniprot IDs		Q16378	B0QY95 Q9NQG6
PDB IDs			4NXT 4NXU 4NXV 4NXW 4NXX 5X9B 5X9C
Enriched GO Terms of Interacting Partners?		Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Molecular Condensate Scaffold Activity Localization Within Membrane TCR Signalosome Autophagosome Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Organization Autophagosome Assembly ERAD Pathway Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Store-operated Calcium Channel Activity TRC Complex Positive Regulation Of Proteolysis Involved In Protein Catabolic Process GET Complex Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Clathrin-dependent Endocytosis Identical Protein Binding Positive Regulation Of Mitochondrial Fusion Vacuole Organization Positive Regulation Of Protein Metabolic Process Regulation Of Macroautophagy Establishment Of Protein Localization To Membrane Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Membrane Raft Distribution Membrane Raft Localization Response To Endoplasmic Reticulum Stress Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Autophagy Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Mitochondrial Fusion Aggrephagy Mitochondrial Fission Membrane Insertase Activity Tail-anchored Membrane Protein Insertion Into ER Membrane Negative Regulation Of Receptor Internalization Positive Regulation Of Protein Modification Process Regulation Of Protein Catabolic Process Regulation Of Autophagy Regulation Of Clathrin-dependent Endocytosis Mitochondrial Fusion Regulation Of Proteolysis Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Positive Regulation Of Mitochondrial Fission
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?