FILIP1L and SMTN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FILIP1L	SMTN
Description		filamin A interacting protein 1 like	smoothelin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Actin Cytoskeleton Membrane	Cytoplasm Cytoskeleton Actin Cytoskeleton
	Molecular Function	Protein Binding	Actin Binding Protein Binding Structural Constituent Of Muscle
	Biological Process	Protein Localization To Actin Cytoskeleton	Smooth Muscle Contraction Muscle Organ Development
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Age-related macular degeneration ( 23455636) Axial length ( 24144296) Breast cancer ( 29059683) Optic disc size ( 31809533) Refractive error ( 32231278) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	A body shape index ( 34021172) Bulimia nervosa ( 23568457) Fish- and plant-related diet ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		2 interacting genes: FBXL17 SMTN	3 interacting genes: ACTA1 BRMS1 FILIP1L
Entrez ID		11259	6525
HPRD ID		16832	03675
Ensembl ID		ENSG00000168386	ENSG00000183963
Uniprot IDs		H7C4M0 Q4L180	A0A087WVP4 A0A087X1R1 B4DI56 B4E229 P53814
PDB IDs			2D87
Enriched GO Terms of Interacting Partners?			Actin Cytoskeleton Skeletal Muscle Thin Filament Assembly Mesenchyme Migration Protein Localization To Actin Cytoskeleton Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis Striated Muscle Thin Filament Regulation Of Protein Deacetylation Skeletal Muscle Fiber Development Myosin Binding Sin3-type Complex Regulation Of Anoikis Negative Regulation Of Stem Cell Population Maintenance Myotube Cell Development NF-kappaB Binding
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