DMC1 and RAD54B

Number of citations of the paper that reports this interaction (PMID 15164066)
47

Data Source:
HPRD (in vitro)

		DMC1	RAD54B
Gene Name		DNA meiotic recombinase 1	RAD54 homolog B (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nucleus Chromosome	Nucleus
	Molecular Function	DNA Binding Protein Binding ATP Binding DNA-dependent ATPase Activity	DNA Binding DNA Helicase Activity RNA Helicase Activity ATP Binding DNA Translocase Activity
	Biological Process	Ovarian Follicle Development Oocyte Maturation Meiotic Nuclear Division Synapsis Reciprocal Meiotic Recombination Male Meiosis I Spermatogenesis Spermatid Development Female Gamete Generation	Double-strand Break Repair Via Homologous Recombination Mitotic Recombination Reciprocal Meiotic Recombination DNA Duplex Unwinding
Pathways		Meiotic recombination
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: BRCA2 GORASP2 KCTD17 NIF3L1 PSMA3 RAD51 RAD54B RPA1 SDCBP TRIM23	26 interactors: ANKRD36BP1 ATPAF2 CCDC33 CDC23 CSNK1E DMC1 DYRK2 ENKD1 GMCL1 GORASP2 LNX1 MDM4 MYO15B NIF3L1 NUDT18 PRKAA1 PSMA1 RAD51 RIBC2 SUMO1 TCEANC TCEB3 TRAPPC6A UBE2I WRN ZNF580
Entrez ID		11144	25788
HPRD ID		04099	05049
Ensembl ID		ENSG00000100206	ENSG00000197275
Uniprot IDs		B4DMW6 Q14565	O95073 Q9Y620
PDB IDs		1V5W 2ZJB 4HYY
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Via Homologous Recombination Recombinational Repair Mitotic Recombination Double-strand Break Repair Meiotic Nuclear Division Meiotic Cell Cycle DNA Recombinase Assembly DNA Recombination Cell Cycle Meiosis I DNA-dependent DNA Replication Cellular Response To DNA Damage Stimulus Cell Cycle Process DNA Repair Reciprocal Meiotic Recombination DNA Replication Cellular Response To Stress DNA Duplex Unwinding DNA Geometric Change DNA Damage Response, Signal Transduction By P53 Class Mediator Chromosome Organization Reproduction DNA Metabolic Process Signal Transduction In Response To DNA Damage Nucleotide-excision Repair Organelle Organization 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Signal Transduction By P53 Class Mediator Positive Regulation Of Metabolic Process Positive Regulation Of DNA Ligation Dihydrobiopterin Metabolic Process Cellular Response To Camptothecin Response To Ionizing Radiation Response To Camptothecin Positive Regulation Of Extracellular Vesicular Exosome Assembly G1/S Transition Of Mitotic Cell Cycle Protein-DNA Complex Assembly Positive Regulation Of Cellular Metabolic Process Regulation Of Extracellular Vesicular Exosome Assembly Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Mitotic Cell Cycle Replication Fork Protection Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Homooligomerization Response To UV-C Substrate-dependent Cell Migration, Cell Extension Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Intracellular Signal Transduction	Cell Cycle Cell Cycle Process Cellular Response To Stress Response To Camptothecin Cellular Response To DNA Damage Stimulus Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Metabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Proteolysis Signal Transduction By P53 Class Mediator Protein Modification By Small Protein Conjugation Positive Regulation Of Cellular Metabolic Process Protein Sumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Ionizing Radiation Regulation Of Metabolic Process Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Proteasomal Protein Catabolic Process Reciprocal Meiotic Recombination Ubiquitin-dependent Protein Catabolic Process DGDP Catabolic Process DADP Catabolic Process GDP Catabolic Process Response To Brefeldin A Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Positive Regulation Of SUMO Transferase Activity Modification-dependent Protein Catabolic Process Organelle Organization Response To Gamma Radiation Chromosome Segregation Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle DNA Recombination Nitrogen Compound Metabolic Process Cellular Response To Ionizing Radiation Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Proteolysis Involved In Cellular Protein Catabolic Process Peptidyl-amino Acid Modification Cellular Response To Hydrogen Peroxide Heterocycle Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transferase Activity Cellular Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Proteasomal Protein Catabolic Process
Tagcloud ?		abs beams bragg btg2 ccnb2 cdc25a cdc25c exo1 fen1 gadd45a gtse1 gy hle ifnb1 instantaneous karyotyping mdm4 mm2 passively prc1 protons pttg1 rpa1 siah1 tdr voxel xrcc2 xrcc3 xrcc6bp1	behind checkpoint checkpoints constitutive critically ddr downregulated dynamically facilitating fate fine g2 helicase influences instability integrity ligase limiting limits maintaining mdm2 mdmx override phases scaffold scaffolding snf2 strength tuning
Tagcloud (Difference) ?		abs beams bragg btg2 ccnb2 cdc25a cdc25c exo1 fen1 gadd45a gtse1 gy hle ifnb1 instantaneous karyotyping mdm4 mm2 passively prc1 protons pttg1 rpa1 siah1 tdr voxel xrcc2 xrcc3 xrcc6bp1	behind checkpoint checkpoints constitutive critically ddr downregulated dynamically facilitating fate fine g2 helicase influences instability integrity ligase limiting limits maintaining mdm2 mdmx override phases scaffold scaffolding snf2 strength tuning
Tagcloud (Intersection) ?