RER1 and SYT16

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RER1	SYT16
Description		retention in endoplasmic reticulum sorting receptor 1	synaptotagmin 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Plasma Membrane Cell Surface Membrane
	Molecular Function	Protein Binding Acetylcholine Receptor Binding	Protein Binding Phospholipid Binding Identical Protein Binding
	Biological Process	Protein Retention In ER Lumen Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Neuromuscular Junction Development Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Metabolite levels ( 23823483) Serum alkaline phosphatase levels ( 33547301) Vitamin C levels ( 33203707)	Adult body size ( 32376654) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Chronotype ( 30696823) Estimated glomerular filtration rate after 1 year in renal transplantation (recipient effect) ( 30920136) Hepatitis ( 25705159) Longevity (90 years and older) ( 24688116) Recurrence of mild malaria attacks ( 31667592) Self-rated health ( 20707712) Telomere length ( 24478790)
Interacting Genes		6 interacting genes: HAP1 IMMT SCAND1 SH3GL3 SYT16 WIPF1	29 interacting genes: AGTRAP APOC1 APOC2 APOC4 C10orf67 CMTM5 CYSTM1 DERL3 FGF14 GSG1 HIGD1C LDAF1 MPC2 MTFR1 NCOA5 PHC2 PLEKHF2 RABAC1 REEP6 RER1 RHBDD2 RPRM RTN4 SDR16C5 SFT2D1 SYT14 TMEM239 TVP23B ZBTB14
Entrez ID		11079	83851
HPRD ID		17967	15461
Ensembl ID		ENSG00000157916	ENSG00000139973
Uniprot IDs		O15258 Q5T094	Q17RD7
PDB IDs
Enriched GO Terms of Interacting Partners?			High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Acylglycerol Homeostasis Triglyceride Homeostasis Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Signal Recognition Particle Binding Endoplasmic Reticulum Lipid Homeostasis Chylomicron Phospholipid Efflux Endoplasmic Reticulum Membrane Negative Regulation Of Lipoprotein Particle Clearance Negative Regulation Of Cholesterol Transport Plasma Lipoprotein Particle Clearance Lipoprotein Metabolic Process Regulation Of Phospholipid Metabolic Process Cholesterol Efflux Plasma Lipoprotein Particle Remodeling Negative Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Phosphatidylcholine Catabolic Process Membrane Negative Regulation Of Vasculogenesis Positive Regulation Of ERBB3 Signaling Pathway Cell Adhesion Involved In Sprouting Angiogenesis Protein-containing Complex Remodeling Negative Regulation Of Lipid Transport Regulation Of Triglyceride Metabolic Process
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