OGFR and ACKR5

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		OGFR	ACKR5
Description		opioid growth factor receptor	atypical chemokine receptor 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Membrane	Plasma Membrane Membrane
	Molecular Function	Protein Binding Signaling Receptor Activity Opioid Growth Factor Receptor Activity	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity
	Biological Process	Regulation Of Cell Growth	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Creatinine levels ( 29124443) Estimated glomerular filtration rate ( 29124443) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		3 interacting genes: ACKR5 TERF1 TERF2IP	10 interacting genes: ABHD12 GOSR1 HLA-C ITGA5 MPG OGFR PLPPR3 TMEM101 TMEM30A TMUB2
Entrez ID		11054	11318
HPRD ID		08404	05605
Ensembl ID		ENSG00000060491	ENSG00000166856
Uniprot IDs		Q9NZT2	O15218
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear Telomere Cap Complex Shelterin Complex G-rich Strand Telomeric DNA Binding Telomere Capping Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Telomeric DNA Binding Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization DNA Biosynthetic Process Telomere Maintenance Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Telomere Organization Positive Regulation Of Shelterin Complex Assembly Negative Regulation Of DNA Metabolic Process Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Chromosome, Telomeric Region Negative Regulation Of DNA Recombination At Telomere Regulation Of Chromosome Organization Positive Regulation Of DNA Metabolic Process Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Telomerase Activity Chromosome Organization Ankyrin Repeat Binding Protection From Non-homologous End Joining At Telomere Nuclear Body Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Telomere Localization Telomeric D-loop Disassembly Double-stranded Telomeric DNA Binding Telomeric Loop Disassembly Protein Localization To Chromosome, Telomeric Region T-circle Formation Regulation Of DNA Metabolic Process Telomere Maintenance In Response To DNA Damage Positive Regulation Of Organelle Organization DNA Binding, Bending Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of DNA Replication Chromosome Negative Regulation Of Cellular Component Organization
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