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SLC27A2 and AP4E1
SLC27A2
AP4E1
Description
solute carrier family 27 member 2
adaptor related protein complex 4 subunit epsilon 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Peroxisome
Peroxisomal Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Lumen
Endoplasmic Reticulum Membrane
Cytosol
Plasma Membrane
Membrane
Specific Granule Membrane
Extracellular Exosome
Golgi Apparatus
Trans-Golgi Network
Membrane
Membrane Coat
AP-4 Adaptor Complex
Endosome Lumen
Trans-Golgi Network Membrane
Molecular Function
Nucleotide Binding
Long-chain Fatty Acid-CoA Ligase Activity
Long-chain Fatty Acid Transmembrane Transporter Activity
ATP Binding
Fatty Acid Transmembrane Transporter Activity
Ligase Activity
Enzyme Binding
Very Long-chain Fatty Acid-CoA Ligase Activity
Arachidonate-CoA Ligase Activity
Cholate-CoA Ligase Activity
Phytanate-CoA Ligase Activity
Pristanate-CoA Ligase Activity
Protein Binding
Cargo Adaptor Activity
Biological Process
Very Long-chain Fatty Acid Metabolic Process
Fatty Acid Alpha-oxidation
Long-chain Fatty Acid Metabolic Process
Lipid Metabolic Process
Fatty Acid Metabolic Process
Fatty Acid Beta-oxidation
Bile Acid Biosynthetic Process
Lipid Transport
Bile Acid Metabolic Process
Fatty Acid Transport
Long-chain Fatty Acid Transport
Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Very Long-chain Fatty Acid Catabolic Process
Long-chain Fatty Acid Import Into Cell
Fatty-acyl-CoA Biosynthetic Process
Methyl-branched Fatty Acid Metabolic Process
Protein Targeting
Intracellular Protein Transport
Intracellular Protein Localization
Protein Transport
Vesicle-mediated Transport
Establishment Of Protein Localization
Pathways
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Synthesis of bile acids and bile salts via 24-hydroxycholesterol
Alpha-oxidation of phytanate
Beta-oxidation of very long chain fatty acids
Neutrophil degranulation
Fatty acyl-CoA biosynthesis
Peroxisomal protein import
Peroxisomal protein import
Lysosome Vesicle Biogenesis
Golgi Associated Vesicle Biogenesis
Drugs
Diseases
Cerebral palsy
GWAS
Platelet count (
32888494
)
Verbal declarative memory (
25648963
)
Chloride levels (
29403010
)
Creatinine levels (
29403010
)
Glomerular filtration rate (
29403010
)
Height (
31562340
)
Keratoconus (
33649486
)
Potassium levels (
29403010
)
Response to fenofibrate (HDL cholesterol levels) (
27002377
)
Interacting Genes
4 interacting genes:
ABCD1
PEX5
UBC
YWHAQ
3 interacting genes:
AP4B1
ARF1
MTNR1B
Entrez ID
11001
23431
HPRD ID
11935
06258
Ensembl ID
ENSG00000140284
ENSG00000081014
Uniprot IDs
O14975
B4DM48
Q9UPM8
PDB IDs
Enriched GO Terms of Interacting Partners
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Protein Targeting
Cleavage Furrow Ingression
Mitotic Cleavage Furrow Ingression
Cytoplasmic Side Of Trans-Golgi Network Transport Vesicle Membrane
Protein Localization To Somatodendritic Compartment
Pristanate-CoA Ligase Activity
Phytanate-CoA Ligase Activity
Cholate-CoA Ligase Activity
Melatonin Receptor Activity
Positive Regulation Of Transmission Of Nerve Impulse
Positive Regulation Of Circadian Sleep/wake Cycle, Sleep
Negative Regulation Of CGMP-mediated Signaling
Regulation Of Neuronal Action Potential
Negative Regulation Of Transmission Of Nerve Impulse
Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep
Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep
AP-4 Adaptor Complex
Fatty Acid Transmembrane Transporter Activity
Very Long-chain Fatty Acid Catabolic Process
Methyl-branched Fatty Acid Metabolic Process
Fatty Acid Alpha-oxidation
Very Long-chain Fatty Acid-CoA Ligase Activity
Arachidonate-CoA Ligase Activity
Long-chain Fatty Acid Import Into Cell
Negative Regulation Of Vasoconstriction
Regulation Of CGMP-mediated Signaling
Clathrin Adaptor Complex
Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Intracellular Copper Ion Homeostasis
Long-term Synaptic Depression
Negative Regulation Of Cytosolic Calcium Ion Concentration
Long-chain Fatty Acid Transmembrane Transporter Activity
Long-chain Fatty Acid-CoA Ligase Activity
Lipid Import Into Cell
Regulation Of Transmission Of Nerve Impulse
Copper Ion Homeostasis
Negative Regulation Of Nervous System Process
Regulation Of Circadian Sleep/wake Cycle, Sleep
Positive Regulation Of Circadian Rhythm
Regulation Of Circadian Sleep/wake Cycle
Endosome Lumen
Bile Acid Biosynthetic Process
Intracellular Protein Transport
Mitotic Cytokinetic Process
Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Fatty-acyl-CoA Biosynthetic Process
Positive Regulation Of Behavior
Membrane Coat
Dendritic Spine Organization
Bile Acid Metabolic Process
Regulation Of Actin Nucleation
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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