SLC27A2 and PDCD11

		SLC27A2	PDCD11
Description		solute carrier family 27 member 2	programmed cell death 11
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Specific Granule Membrane Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Cytosol Small-subunit Processome
	Molecular Function	Nucleotide Binding Long-chain Fatty Acid-CoA Ligase Activity Long-chain Fatty Acid Transmembrane Transporter Activity ATP Binding Fatty Acid Transmembrane Transporter Activity Ligase Activity Enzyme Binding Very Long-chain Fatty Acid-CoA Ligase Activity Arachidonate-CoA Ligase Activity Cholate-CoA Ligase Activity Phytanate-CoA Ligase Activity Pristanate-CoA Ligase Activity	Nucleic Acid Binding RNA Binding Protein Binding NF-kappaB Binding
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Fatty Acid Alpha-oxidation Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Bile Acid Biosynthetic Process Lipid Transport Bile Acid Metabolic Process Fatty Acid Transport Long-chain Fatty Acid Transport Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Very Long-chain Fatty Acid Catabolic Process Long-chain Fatty Acid Import Into Cell Fatty-acyl-CoA Biosynthetic Process Methyl-branched Fatty Acid Metabolic Process	RRNA Processing RNA Processing
Pathways		Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Synthesis of bile acids and bile salts via 24-hydroxycholesterol Alpha-oxidation of phytanate Beta-oxidation of very long chain fatty acids Neutrophil degranulation Fatty acyl-CoA biosynthesis Peroxisomal protein import Peroxisomal protein import	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Platelet count ( 32888494) Verbal declarative memory ( 25648963)	Appendicular lean mass ( 33097823) Autism spectrum disorder or schizophrenia ( 28540026) Estimated glomerular filtration rate ( 31152163) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 23974872 25056061) White matter hyperintensity burden ( 25663218)
Interacting Genes		4 interacting genes: ABCD1 PEX5 UBC YWHAQ	77 interacting genes: ERBB2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NFKB1 RELA RNF10 S100A8
Entrez ID		11001	22984
HPRD ID		11935	18752
Ensembl ID		ENSG00000140284	ENSG00000148843
Uniprot IDs		O14975	A0A3B3IUD7 Q14690
PDB IDs			1WI5
Enriched GO Terms of Interacting Partners?		Protein Targeting	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization Negative Regulation Of Cytokine Production RNA Destabilization Regulation Of Angiogenesis Regulation Of Vasculature Development Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Locomotion Positive Regulation Of MRNA Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Translation Negative Regulation Of Developmental Process Regulation Of MRNA Stability Regulation Of RNA Stability Extracellular Space Negative Regulation Of Protein Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Endothelial Cell Migration Regulation Of Cytokine Production Regulation Of Cell Migration Negative Regulation Of Signal Transduction Regulation Of Anatomical Structure Morphogenesis Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Motility
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