EBNA1BP2 and FGF3

Number of citations of the paper that reports this interaction (PubMedID 11438656)
39

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		EBNA1BP2	FGF3
Description		EBNA1 binding protein 2	fibroblast growth factor 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Chromosome Nucleolus Preribosome, Large Subunit Precursor Nuclear Periphery	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	RNA Binding Protein Binding	Fibroblast Growth Factor Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	RRNA Processing Ribosome Biogenesis Ribosomal Large Subunit Biogenesis	Signal Transduction Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Anatomical Structure Morphogenesis Neurogenesis Cell Differentiation Regulation Of Cell Migration Positive Regulation Of MAPK Cascade Regulation Of Developmental Process Regulation Of Multicellular Organismal Process Positive Regulation Of Cell Division Negative Regulation Of Cardiac Muscle Tissue Development
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	PI3K Cascade PIP3 activates AKT signaling FGFR1b ligand binding and activation FGFR2b ligand binding and activation Activated point mutants of FGFR2 Constitutive Signaling by Aberrant PI3K in Cancer Phospholipase C-mediated cascade: FGFR1 Phospholipase C-mediated cascade; FGFR2 Downstream signaling of activated FGFR1 SHC-mediated cascade:FGFR1 PI-3K cascade:FGFR1 FRS-mediated FGFR1 signaling PI-3K cascade:FGFR2 SHC-mediated cascade:FGFR2 FRS-mediated FGFR2 signaling Negative regulation of FGFR1 signaling Negative regulation of FGFR2 signaling Signaling by FGFR2 in disease FGFRL1 modulation of FGFR1 signaling RAF/MAP kinase cascade PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs
Diseases			Kaposi's sarcoma
GWAS		Metabolite levels ( 23823483)	Attention deficit hyperactivity disorder ( 29325848) Breast cancer ( 20453838) Childhood ear infection ( 27182965 28928442) Craniofacial microsomia ( 26853712) Lean body mass ( 28552196) Monobrow ( 27182965) Protein quantitative trait loci ( 18464913) Urate levels in overweight individuals ( 25811787) White blood cell count (basophil) ( 29403010)
Interacting Genes		5 interacting genes: CEP70 FAM9B FBXW7 FGF3 GSK3A	6 interacting genes: EBNA1BP2 FGFR1 FGFR2 FGFR3 FGFR4 RPS2
Entrez ID		10969	2248
HPRD ID		16849	01289
Ensembl ID		ENSG00000117395	ENSG00000186895
Uniprot IDs		H7C2Q8 Q6IB29 Q99848	A0A7U3JVY0 P11487
PDB IDs		8FKP 8FKQ 8FKR 8FKS 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY
Enriched GO Terms of Interacting Partners?		Regulation Of Proteasomal Protein Catabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Targeting To Mitochondrion Regulation Of Mitophagy Regulation Of Autophagy Of Mitochondrion Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Regulation Of Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Neuron Apoptotic Process Negative Regulation Of UDP-glucose Catabolic Process Negative Regulation Of Cardiac Muscle Tissue Development Regulation Of Mitochondrion Organization Negative Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Positive Regulation Of Signal Transduction Positive Regulation Of Post-translational Protein Modification Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Parkin-FBXW7-Cul1 Ubiquitin Ligase Complex Negative Regulation Of Hepatocyte Proliferation Phosphothreonine Residue Binding Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Cardiac Muscle Tissue Development Response To Symbiotic Bacterium Response To UV Response To Symbiont Negative Regulation Of Intracellular Signal Transduction Regulation Of Intrinsic Apoptotic Signaling Pathway Phospholipid-hydroperoxide Glutathione Peroxidase Activity Regulation Of Ubiquitin-dependent Protein Catabolic Process Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Regulation Of Microtubule Cytoskeleton Organization Regulation Of Glycogen (starch) Synthase Activity Ubiquitin Recycling Negative Regulation Of SREBP Signaling Pathway Negative Regulation Of Triglyceride Biosynthetic Process Negative Regulation Of Osteoclast Development Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Ubiquitination Regulation Of Macroautophagy Lewy Body Positive Regulation Of Proteolysis Autosome Genomic Imprinting Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway	Fibroblast Growth Factor Binding Fibroblast Growth Factor Receptor Activity Positive Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Catalytic Activity Protein Tyrosine Kinase Activity Fibroblast Growth Factor Receptor Signaling Pathway Involved In Orbitofrontal Cortex Development Regulation Of Catalytic Activity Receptor Complex Ventricular Zone Neuroblast Division Orbitofrontal Cortex Development Peptidyl-tyrosine Phosphorylation Forebrain Neuroblast Division Forebrain Ventricular Zone Progenitor Cell Division Biomineral Tissue Development Lung-associated Mesenchyme Development Endochondral Bone Growth Positive Regulation Of Hydrolase Activity Branching Involved In Salivary Gland Morphogenesis Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Protein Autophosphorylation Positive Regulation Of MAPK Cascade Protein Kinase Activity Bone Growth Heparin Binding Kinase Activity Positive Regulation Of ERK1 And ERK2 Cascade Enzyme-linked Receptor Protein Signaling Pathway Regulation Of MAPK Cascade Mesenchymal Cell Proliferation Positive Regulation Of Mesenchymal Cell Proliferation Positive Regulation Of Cardiac Muscle Cell Proliferation Gland Morphogenesis Cellular Response To Fibroblast Growth Factor Stimulus Midbrain Development Regulation Of Mesenchymal Cell Proliferation Bone Morphogenesis Positive Regulation Of Heart Growth Positive Regulation Of Protein Metabolic Process Response To Fibroblast Growth Factor Ureteric Bud Development Regulation Of Cardiac Muscle Cell Proliferation Regulation Of ERK1 And ERK2 Cascade Mesonephric Tubule Development Positive Regulation Of Cell Population Proliferation Mesonephric Epithelium Development Positive Regulation Of Organ Growth Regulation Of Developmental Growth
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