ACOT2 and INTS4

		ACOT2	INTS4
Description		acyl-CoA thioesterase 2	integrator complex subunit 4
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Peroxisomal Matrix Cytosol	Nucleus Nucleoplasm Nucleolus Cytoplasm Integrator Complex INTAC Complex
	Molecular Function	Protein Binding Hydrolase Activity Thiolester Hydrolase Activity Fatty Acyl-CoA Hydrolase Activity Carboxylic Ester Hydrolase Activity	Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Monocarboxylic Acid Metabolic Process	SnRNA Processing Regulation Of Transcription Elongation By RNA Polymerase II RNA Polymerase II Transcription Initiation Surveillance
Pathways		Mitochondrial Fatty Acid Beta-Oxidation Peroxisomal protein import Peroxisomal protein import Mitochondrial protein degradation	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Urinary metabolite levels in chronic kidney disease ( 31959995)	Mean reticulocyte volume ( 32888494) Platelet count ( 32888494) Tourette syndrome ( 30818990)
Interacting Genes		2 interacting genes: PEX5 SLC13A1	9 interacting genes: HGS KIAA0513 LHX3 MEIS3 PCM1 PYGM RNF10 USHBP1 ZMIZ2
Entrez ID		10965	92105
HPRD ID		10173	12386
Ensembl ID		ENSG00000119673	ENSG00000149262
Uniprot IDs		B3KSA0 P49753	A0A8C8UVZ7 A0A8Q3SHL8 A0A8Q3SHT4 A0A8Q3WKB5 Q96HW7
PDB IDs		3HLK	7BFP 7BFQ 7CUN 7PKS 7YCX 8R2D 8RBX 8RBZ 8RC4 8YJB
Enriched GO Terms of Interacting Partners?		Peroxisome Membrane Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Sodium:sulfate Symporter Activity Monoatomic Anion:sodium Symporter Activity Protein Import Into Peroxisome Matrix, Translocation Peroxisome Targeting Sequence Binding Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Membrane Protein Import Into Peroxisome Matrix, Substrate Release Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix, Receptor Recycling Protein Carrier Chaperone Secondary Active Sulfate Transmembrane Transporter Activity Protein Unfolding Protein Import Into Peroxisome Matrix Pexophagy Sulfate Transmembrane Transport Solute:sodium Symporter Activity INTAC Complex Peroxisomal Membrane Transport Establishment Of Protein Localization To Peroxisome Integrator Complex RNA Polymerase II Transcription Initiation Surveillance Cerebral Cortex Neuron Differentiation Peroxisome Organization Receptor Recycling Intracellular Protein Transmembrane Transport Cerebral Cortex Cell Migration Positive Regulation Of Multicellular Organism Growth SnRNA Processing Very Long-chain Fatty Acid Metabolic Process Nuclear RNA Surveillance Forebrain Neuron Differentiation RNA Surveillance Telencephalon Cell Migration Forebrain Cell Migration Receptor Metabolic Process Peroxisomal Matrix SnRNA Metabolic Process Fatty Acid Beta-oxidation Protein Monoubiquitination Endoplasmic Reticulum Organization Peroxisomal Membrane
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