ACOT2

Description		acyl-CoA thioesterase 2
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Peroxisomal Matrix Cytosol
	Molecular Function	Protein Binding Hydrolase Activity Thiolester Hydrolase Activity Fatty Acyl-CoA Hydrolase Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Monocarboxylic Acid Metabolic Process
Pathways		Mitochondrial Fatty Acid Beta-Oxidation Peroxisomal protein import Peroxisomal protein import Mitochondrial protein degradation
Drugs
Diseases
GWAS		Urinary metabolite levels in chronic kidney disease ( 31959995)
Novel Interacting Genes		1 novel interacting genes: INTS4
Interacting Genes		2 interacting genes: PEX5 SLC13A1
Entrez ID		10965
HPRD ID		10173
Ensembl ID		ENSG00000119673
Uniprot IDs		B3KSA0 P49753
PDB IDs		3HLK
Enriched GO Terms of Interacting Partners?		Peroxisome Membrane Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Sodium:sulfate Symporter Activity Monoatomic Anion:sodium Symporter Activity Protein Import Into Peroxisome Matrix, Translocation Peroxisome Targeting Sequence Binding Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Membrane Protein Import Into Peroxisome Matrix, Substrate Release Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix, Receptor Recycling Protein Carrier Chaperone Secondary Active Sulfate Transmembrane Transporter Activity Protein Unfolding Protein Import Into Peroxisome Matrix Pexophagy Sulfate Transmembrane Transport Solute:sodium Symporter Activity INTAC Complex Peroxisomal Membrane Transport Establishment Of Protein Localization To Peroxisome Integrator Complex RNA Polymerase II Transcription Initiation Surveillance Cerebral Cortex Neuron Differentiation Peroxisome Organization Receptor Recycling Intracellular Protein Transmembrane Transport Cerebral Cortex Cell Migration Positive Regulation Of Multicellular Organism Growth SnRNA Processing Very Long-chain Fatty Acid Metabolic Process Nuclear RNA Surveillance Forebrain Neuron Differentiation RNA Surveillance Telencephalon Cell Migration Forebrain Cell Migration Receptor Metabolic Process Peroxisomal Matrix SnRNA Metabolic Process Fatty Acid Beta-oxidation Protein Monoubiquitination Endoplasmic Reticulum Organization Peroxisomal Membrane
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