ZMYND11 and TCF20

		ZMYND11	TCF20
Description		zinc finger MYND-type containing 11	transcription factor 20
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome	Nucleus Nucleoplasm Nuclear Body
	Molecular Function	DNA Binding Double-stranded DNA Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding Histone H3K36me3 Reader Activity	DNA Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Chromatin Organization Regulation Of Signal Transduction Regulation Of Transcription Elongation By RNA Polymerase II Negative Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of DNA-templated Transcription Negative Regulation Of JNK Cascade Defense Response To Virus Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Malaria ( 31844061)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Antisaccade task score ( 31596458) Arterial stiffness ( 31070453) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 29273807) Chronotype ( 30696823) Cognitive function ( 25644384) Intelligence ( 28530673) Isthmus-cingulate cortex volume ( 31530798) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656 30285260)
Interacting Genes		26 interacting genes: ARHGEF18 BMPR1A DYNLL1 E2F6 EMSY ETS2 EZH1 EZH2 H3-3A H3-4 H4C1 HDAC1 HOXD4 LTBR MAGEC2 MYB NCOR1 PDLIM7 SMAD2 SMAD3 SMARCA4 SRPK1 TAB1 TRAF3 TRAF6 ZHX1	8 interacting genes: AR ESR1 H2AC20 JUN MAPK14 RNF10 RNF4 SMAD1
Entrez ID		10771	6942
HPRD ID		09830	04378
Ensembl ID		ENSG00000015171	ENSG00000100207
Uniprot IDs		A0A0D9SGD6 A0A994J4C0 A0A994J4I8 A0A994J6Y5 B7Z2J6 E7ENI9 Q15326 Q5BJG6 Q5UGI2	Q9UGU0 W5ZR30
PDB IDs		4NS5 5HDA
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Nucleoplasm Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II DNA Binding Chromatin Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Regulation Of MiRNA Transcription Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Endoderm Development Regulation Of MiRNA Metabolic Process Chromatin Organization Negative Regulation Of Metabolic Process Subtelomeric Heterochromatin Formation Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Positive Regulation Of MiRNA Transcription Constitutive Heterochromatin Formation Chordate Embryonic Development Heterochromatin Formation Negative Regulation Of Androgen Receptor Signaling Pathway Cell Differentiation Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of MiRNA Metabolic Process Multicellular Organism Development Positive Regulation Of Transforming Growth Factor Beta Production RNA Polymerase II Core Promoter Sequence-specific DNA Binding Cellular Developmental Process Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Cell Differentiation Histone H3K27 Trimethyltransferase Activity Paraxial Mesoderm Morphogenesis Chromosome, Telomeric Region RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Animal Organ Morphogenesis Positive Regulation Of Macromolecule Metabolic Process	Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Positive Regulation Of MiRNA Transcription Positive Regulation Of Fibroblast Proliferation Positive Regulation Of MiRNA Metabolic Process Estrogen Response Element Binding Prostate Gland Growth Positive Regulation Of Transcription By RNA Polymerase II MAPK Cascade Regulation Of Fibroblast Proliferation Cellular Response To Estrogen Stimulus Mammary Gland Alveolus Development DNA Binding Transcription By RNA Polymerase II Stem Cell Differentiation Positive Regulation Of RNA Biosynthetic Process Prostate Gland Epithelium Morphogenesis Regulation Of Cell Population Proliferation Positive Regulation Of DNA-templated Transcription Estrogen Receptor Signaling Pathway Nuclear Steroid Receptor Activity Negative Regulation Of Cell Population Proliferation Response To Muscle Stretch SMAD Protein Signal Transduction Enzyme Binding Steroid Binding Positive Regulation Of RNA Metabolic Process DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process 14-3-3 Protein Binding Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Cell Population Proliferation Prostate Induction Organ Growth Transcription Coactivator Binding Nuclear Receptor Activity Regulation Of Gene Expression Male Somatic Sex Determination Regulation Of Macromolecule Biosynthetic Process Regulation Of Morphogenesis Of A Branching Structure Transcription Regulator Complex Euchromatin Transcription Cis-regulatory Region Binding Response To Estrogen Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Response To Hormone
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