TRAF3IP2 and MRPL28

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRAF3IP2	MRPL28
Gene Name		TRAF3 interacting protein 2	mitochondrial ribosomal protein L28
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome
	Molecular Function	Protein Binding	Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	B Cell Apoptotic Process Humoral Immune Response Intracellular Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Immunoglobulin Secretion	Translation Organelle Organization Mitochondrial Translation Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways			Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Psoriasis ( 20953188 20953190) Psoriatic arthritis ( 20953186)
Protein-Protein Interactions		18 interactors: CD40 CHUK FHL3 IKBKB IKBKG MAP3K7 MDFI MRPL28 RIMBP3 STK16 TBK1 TRAF1 TRAF2 TRAF3 TRAF5 TRAF6 TRIP6 UBE2V1	12 interactors: APP BANP CDR2 FAM9B HMBOX1 HTR2A IKZF3 OXA1L TEF TRAF3IP2 TRAF4 TUBB3
Entrez ID		10758	10573
HPRD ID		06129	06889
Ensembl ID		ENSG00000056972	ENSG00000086504
Uniprot IDs		O43734	Q13084
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of NF-kappaB Transcription Factor Activity Toll-like Receptor 4 Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of I-kappaB Kinase/NF-kappaB Signaling Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Regulation Of Innate Immune Response Immune Response-regulating Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Signal Transduction Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Immune Response MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Cytokine Production Regulation Of Signal Transduction Positive Regulation Of Cytokine Production Regulation Of Immune Response Positive Regulation Of Immune System Process T Cell Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Regulation Of Signaling Antigen Receptor-mediated Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Innate Immune Response Regulation Of RNA Metabolic Process Activation Of NF-kappaB-inducing Kinase Activity Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Positive Regulation Of NIK/NF-kappaB Signaling Defense Response Regulation Of Gene Expression	Cell Death Death Phospholipase C-activating Serotonin Receptor Signaling Pathway Synaptic Growth At Neuromuscular Junction Mitochondrial Proton-transporting ATP Synthase Complex Assembly Collateral Sprouting In Absence Of Injury Proton-transporting ATP Synthase Complex Assembly Positive Regulation Of Phosphatidylinositol Biosynthetic Process Regulation Of Protein Binding Cellular Localization Collateral Sprouting Axon Midline Choice Point Recognition Adult Behavior Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Immunoglobulin Secretion Positive Regulation Of Phospholipid Biosynthetic Process Axon Choice Point Recognition Regulation Of Protein Kinase Activity Positive Regulation Of Cellular Biosynthetic Process Artery Smooth Muscle Contraction Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of ATPase Activity Tonic Smooth Muscle Contraction B Cell Apoptotic Process Regulation Of Kinase Activity Positive Regulation Of Intracellular Signal Transduction Neuron Remodeling Positive Regulation Of Protein Homodimerization Activity Urinary Bladder Smooth Muscle Contraction Regulation Of Binding Learning Or Memory Positive Regulation Of Glycolytic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Protein Localization Serotonin Receptor Signaling Pathway Vascular Smooth Muscle Contraction Behavioral Response To Cocaine RNA Metabolic Process Cognition Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial Respiratory Chain Complex I Biogenesis Negative Regulation Of Synaptic Transmission, Glutamatergic Apoptotic Process Cellular Calcium Ion Homeostasis Sleep Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Calcium Ion Homeostasis Programmed Cell Death
Tagcloud ?		acting aligned autoimmunity coevolution competitive disordered dn ds estimations evolved fall hosts interacting likelihood mammalian mammals nonsynonymous ordered outside pathogens plausible pressures purifying selection subject substitution synonymous terminus	asexual candida cerevisiae chromosome cluster coding contains else equivalent exclude fourth gcn3 glabrata his3 homologues includes kb mating mfa1 pathogenic rearrangement saccharomyces section sequenced somewhere stp1 tfb3 xi xv
Tagcloud (Difference) ?		acting aligned autoimmunity coevolution competitive disordered dn ds estimations evolved fall hosts interacting likelihood mammalian mammals nonsynonymous ordered outside pathogens plausible pressures purifying selection subject substitution synonymous terminus	asexual candida cerevisiae chromosome cluster coding contains else equivalent exclude fourth gcn3 glabrata his3 homologues includes kb mating mfa1 pathogenic rearrangement saccharomyces section sequenced somewhere stp1 tfb3 xi xv
Tagcloud (Intersection) ?