TRAF3IP2

Gene Name		TRAF3 interacting protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component
	Molecular Function	Protein Binding
	Biological Process	B Cell Apoptotic Process Humoral Immune Response Intracellular Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Immunoglobulin Secretion
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Psoriasis ( 20953188 20953190) Psoriatic arthritis ( 20953186)
Protein-protein Interactions		18 interactors: CD40 CHUK FHL3 IKBKB IKBKG MAP3K7 MDFI MRPL28 RIMBP3 STK16 TBK1 TRAF1 TRAF2 TRAF3 TRAF5 TRAF6 TRIP6 UBE2V1
Entrez ID		10758
HPRD ID		06129
Ensembl ID		ENSG00000056972
Uniprot IDs		O43734
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of NF-kappaB Transcription Factor Activity Toll-like Receptor 4 Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of I-kappaB Kinase/NF-kappaB Signaling Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Regulation Of Innate Immune Response Immune Response-regulating Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Signal Transduction Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Immune Response MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Cytokine Production Regulation Of Signal Transduction Positive Regulation Of Cytokine Production Regulation Of Immune Response Positive Regulation Of Immune System Process T Cell Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Regulation Of Signaling Antigen Receptor-mediated Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Innate Immune Response Regulation Of RNA Metabolic Process Activation Of NF-kappaB-inducing Kinase Activity Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Positive Regulation Of NIK/NF-kappaB Signaling Defense Response Regulation Of Gene Expression
Tagcloud ?		acting aligned autoimmunity coevolution competitive disordered dn ds estimations evolved fall hosts interacting likelihood mammalian mammals nonsynonymous ordered outside pathogens plausible pressures purifying selection subject substitution synonymous terminus