PTTG2 and RCOR3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PTTG2	RCOR3
Description		pituitary tumor-transforming 2	REST corepressor 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Histone Deacetylase Complex Nucleus Nucleoplasm Transcription Regulator Complex Cytosol
	Molecular Function	Protein Binding SH3 Domain Binding	Transcription Corepressor Activity Protein Binding
	Biological Process	Homologous Chromosome Segregation Chromosome Organization	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Periodontal microbiota ( 22699663) Response to antidepressants (symptom remission) ( 29160301) Response to SSRI (symptom remission) ( 29160301)	Plateletcrit ( 32888494)
Interacting Genes		13 interacting genes: AGR2 APP CRYAA CSNK2B EML2 PRR20A PRR20B PRR20C PRR20D PRR20E RCOR3 RIPPLY1 SUOX	73 interacting genes: ABI1 ANKRD11 APP BORCS6 CBY2 CCDC102B CCDC106 CCHCR1 CDR2 CEP55 CEP63 CEP70 EFHC2 FAM81A FSD2 GKAP1 GLRX3 GOLGA2 GPRASP3 GRIPAP1 GSE1 HAUS3 HMBOX1 HOOK2 HSF2BP ICA1L IKZF3 ING5 ISY1-RAB43 KDM1A KRT15 KRT18 KRT19 KRT24 KRT27 KRT31 KRT40 KRT75 LCA5 LHX3 LUZP4 LZTS2 MAGEA6 MCC MESD MID2 MIPOL1 MTUS2 NDUFB7 NECAB2 NINL NRDE2 NUTM1 PHF19 PIH1D1 PRDM14 PTTG2 STN1 SUMO2 TFIP11 TRAF1 TRAF2 TRIM27 TRIM42 TRIM54 TSGA10 TULP3 TXLNA USHBP1 VAX1 YWHAQ ZNF383 ZNF688
Entrez ID		10744	55758
HPRD ID		09176	08338
Ensembl ID		ENSG00000250254	ENSG00000117625
Uniprot IDs		Q9NZH5	Q9P2K3
PDB IDs			4CZZ
Enriched GO Terms of Interacting Partners?			Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Cytoskeleton Intermediate Filament Organization Intermediate Filament Structural Molecule Activity Protein Binding Identical Protein Binding Supramolecular Fiber Organization Microtubule TORC1 Complex Assembly Cytoskeleton Organization Epithelial Cell Differentiation Microtubule-based Process Telomeric DNA Binding Centrosome
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