TCFL5 and USF1

Number of citations of the paper that reports this interaction (PubMedID 12923186)
0

Data Source:
BioGRID (pull down)

		TCFL5	USF1
Description		transcription factor like 5	upstream transcription factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Male Germ Cell Nucleus Nucleus	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Golgi Apparatus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Double-stranded DNA Binding DNA-binding Transcription Factor Activity Protein Binding Enzyme Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding BHLH Transcription Factor Binding Sequence-specific DNA Binding Protein-containing Complex Binding Protein Heterodimerization Activity Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Transcription By RNA Polymerase II Spermatogenesis Cell Differentiation Regulation Of Cell Population Proliferation Regulation Of Cell Differentiation	Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Response To Hypoxia Glucose Metabolic Process Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Response To UV Glucose Mediated Signaling Pathway Late Viral Transcription Cellular Response To Insulin Stimulus Glucose Homeostasis Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Carbon Catabolite Regulation Of Transcription Negative Regulation Of Fibrinolysis Lipid Homeostasis Cellular Response To Glucose Stimulus
Pathways			Estrogen-dependent gene expression Regulation of MITF-M-dependent genes involved in pigmentation
Drugs
Diseases			Familial combined hyperlipidemia (FCHL)
GWAS		Obesity-related traits ( 23251661)	Granulocyte percentage of myeloid white cells ( 27863252) Inflammatory bowel disease ( 23128233) Night sleep phenotypes ( 27126917)
Interacting Genes		2 interacting genes: TOPBP1 USF1	20 interacting genes: APP ESR1 FBXO7 FOS FOSL1 GTF2I HDAC9 HOMEZ LAP3 MAP3K7CL NFYA PLEKHF2 PPARGC1A PRKDC SNW1 TAOK2 TCF3 TCFL5 TRAF2 USF2
Entrez ID		10732	7391
HPRD ID		05297	01880
Ensembl ID		ENSG00000101190	ENSG00000158773
Uniprot IDs		Q86TP4 Q9UL49	A0A0S2Z4U5 P22415
PDB IDs			1AN4
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Glucose Mediated Signaling Pathway Late Viral Transcription Response To Radiation Positive Regulation Of Transcription By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Viral Transcription BRCA1-B Complex Broken Chromosome Clustering Carbon Catabolite Regulation Of Transcription Carbohydrate Mediated Signaling Regulation Of Transcription By Glucose Double-strand Break Repair Via Alternative Nonhomologous End Joining Phosphorylation-dependent Protein Binding Mitotic DNA Replication Checkpoint Signaling Double-strand Break Repair Via Classical Nonhomologous End Joining Negative Regulation Of Fibrinolysis Regulation Of Fibrinolysis Chromatin-protein Adaptor Activity DNA Replication Checkpoint Signaling Positive Regulation Of Blood Coagulation Protein Localization To Site Of Double-strand Break DNA Replication Initiation BHLH Transcription Factor Binding Positive Regulation Of Coagulation Mitotic G2 DNA Damage Checkpoint Signaling Cellular Response To Nutrient Homologous Recombination Site Of DNA Damage Condensed Nuclear Chromosome Male Germ Cell Nucleus Mitotic G2/M Transition Checkpoint Positive Regulation Of Wound Healing Cellular Response To Glucose Stimulus Cellular Response To Carbohydrate Stimulus Regulation Of Hemostasis Regulation Of Blood Coagulation Mitotic DNA Integrity Checkpoint Signaling Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G2/M Phase Transition Double-strand Break Repair Via Nonhomologous End Joining Mitotic DNA Damage Checkpoint Signaling Protein Serine/threonine Kinase Activator Activity Intracellular Glucose Homeostasis Identical Protein Binding Cellular Response To Insulin Stimulus Site Of Double-strand Break DNA Damage Checkpoint Signaling Protein Localization To Chromosome Regulation Of G2/M Transition Of Mitotic Cell Cycle	Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II RNA Polymerase II-specific DNA-binding Transcription Factor Binding Chromatin Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity Positive Regulation Of RNA Metabolic Process Nucleoplasm Nucleus DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of MiRNA Transcription Cellular Response To Oxygen-containing Compound Regulation Of MiRNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Transcription Regulator Complex Regulation Of Gene Expression Positive Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Transcription By RNA Polymerase II Protein-DNA Complex RNA Polymerase II Transcription Regulator Complex B Cell Lineage Commitment Regulation Of Developmental Process Regulation Of Primary Metabolic Process Mononuclear Cell Differentiation Leukocyte Activation Immunoglobulin V(D)J Recombination Positive Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Leukocyte Differentiation Enzyme Binding Cell Activation RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process RNA Metabolic Process DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Macromolecule Metabolic Process Regulation Of Multicellular Organismal Process Lymphocyte Activation Mitogen-activated Protein Kinase Kinase Kinase Binding Protein-containing Complex
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