RRH and LARP7

		RRH	LARP7
Description		retinal pigment epithelium-derived rhodopsin homolog	La ribonucleoprotein 7, transcriptional regulator
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleus Nucleoplasm Cytosol 7SK SnRNP Ribonucleoprotein Complex
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Photoreceptor Activity Photoreceptor Activity	Nucleic Acid Binding RNA Binding Protein Binding U6 SnRNA Binding 7SK SnRNA Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Visual Perception Phototransduction Detection Of Visible Light Cellular Response To Light Stimulus	Negative Regulation Of Transcription By RNA Polymerase II Box C/D Sno(s)RNA 3'-end Processing RNA Processing MRNA Processing Spermatogenesis RNA Splicing Cell Differentiation Negative Regulation Of Viral Transcription Negative Regulation Of Transcription Elongation By RNA Polymerase II Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of SnRNA Transcription By RNA Polymerase II U6 2'-O-snRNA Methylation
Pathways		G alpha (i) signalling events Opsins
Drugs
Diseases
GWAS			Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Dental caries (decayed and filled deciduous teeth) ( 31533690) Meat-related diet ( 32066663) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		2 interacting genes: NSG2 TGFBR1	79 interacting genes: APP BARD1 BRCA1 JMJD6 LRRK2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PRPF40A RN7SK WEE2-AS1
Entrez ID		10692	51574
HPRD ID		05565	17095
Ensembl ID		ENSG00000180245	ENSG00000174720
Uniprot IDs		O14718	A0A8I5KUI4 A0A8Q3SHH4 A0A8Q3SHN7 H0YA82 Q4G0J3
PDB IDs			4WKR 5KNW 6D12 7SLP 7SLQ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Proepicardium Development Angiogenesis Involved In Coronary Vascular Morphogenesis Positive Regulation Of Tight Junction Disassembly Vascular Endothelial Cell Proliferation Epicardium Morphogenesis Transforming Growth Factor Beta Ligand-receptor Complex Box C/D Sno(s)RNA 3'-end Processing U6 2'-O-snRNA Methylation Positive Regulation Of SnRNA Transcription By RNA Polymerase II 7SK SnRNP Golgi Cis Cisterna Membrane Positive Regulation Of Mesenchymal Stem Cell Proliferation Myofibroblast Differentiation Activin Receptor Complex Activin Receptor Activity, Type I Type II Transforming Growth Factor Beta Receptor Binding Ventricular Compact Myocardium Morphogenesis Coronary Artery Morphogenesis Parathyroid Gland Development Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Germ Cell Migration Positive Regulation Of Extracellular Matrix Assembly Transforming Growth Factor Beta Receptor Activity Trophoblast Cell Migration Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Endothelial Cell Activation Transforming Growth Factor Beta Receptor Activity, Type I SnRNA Modification 7SK SnRNA Binding Positive Regulation Of Protein Localization To Cajal Body Clathrin Light Chain Binding Coronary Vasculature Morphogenesis Activin Binding Transmembrane Receptor Protein Serine/threonine Kinase Activity U6 SnRNA Binding Ventricular Trabecula Myocardium Morphogenesis I-SMAD Binding Negative Regulation Of Viral Transcription Sno(s)RNA Metabolic Process Pharyngeal System Development Serine/threonine Protein Kinase Complex Regulation Of Viral Transcription Clathrin Coat Assembly Heart Trabecula Morphogenesis Transforming Growth Factor Beta Binding Regulation Of Extracellular Matrix Assembly Filopodium Assembly Negative Regulation Of Transcription Elongation By RNA Polymerase II Negative Regulation Of Chondrocyte Differentiation	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Metabolic Process Extracellular Vesicle Negative Regulation Of Translation MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Angiogenesis Negative Regulation Of Cell Migration Regulation Of Gene Expression Regulation Of Vasculature Development Negative Regulation Of Angiogenesis Negative Regulation Of Cytokine Production Negative Regulation Of Vasculature Development Negative Regulation Of Cell Motility Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Locomotion Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Translation Regulation Of MRNA Stability Regulation Of Macromolecule Metabolic Process Regulation Of RNA Stability Negative Regulation Of Multicellular Organismal Process Regulation Of MRNA Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Extracellular Space Negative Regulation Of Protein Metabolic Process Regulation Of Endothelial Cell Migration Negative Regulation Of Developmental Process Negative Regulation Of Signal Transduction Regulation Of Metabolic Process Regulation Of Cytokine Production Regulation Of Cell Migration Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Locomotion
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