RPP38 and POP7

Number of citations of the paper that reports this interaction (PubMedID 9630247)
33

Data Source:
HPRD (in vivo)

		RPP38	POP7
Description		ribonuclease P/MRP subunit p38	POP7 ribonuclease P/MRP subunit
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GO Annotations	Cellular Component	Ribonuclease MRP Complex Fibrillar Center Nucleus Nucleoplasm Nucleolar Ribonuclease P Complex Nucleolus Multimeric Ribonuclease P Complex	Ribonuclease MRP Complex Nucleus Nucleoplasm Nucleolar Ribonuclease P Complex Nucleolus Cytoplasm Multimeric Ribonuclease P Complex
	Molecular Function	RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding	Nucleic Acid Binding RNA Binding Ribonuclease P Activity Protein Binding Ribonuclease P RNA Binding
	Biological Process	TRNA 5'-leader Removal RRNA Processing TRNA Processing	TRNA 5'-leader Removal RRNA Processing RNA Processing TRNA Processing
Pathways		tRNA processing in the nucleus Major pathway of rRNA processing in the nucleolus and cytosol	tRNA processing in the nucleus
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis ( 25187353) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin concentration ( 27863252) Low density lipoprotein cholesterol levels ( 32154731) Medication use (thyroid preparations) ( 31015401) Pursuit maintenance gain in psychotic disorders ( 29064472) Red blood cell count ( 27863252 32888494) Schizophrenia ( 30285260)
Interacting Genes		9 interacting genes: POP1 POP4 POP7 PTEN RPP14 RPP21 RPP25 RPP30 RPP40	11 interacting genes: AKT1 APP C9orf72 FOXP1 HSPB1 LAGE3 RPP25 RPP25L RPP38 RPP40 SMN1
Entrez ID		10557	10248
HPRD ID		09360	09357
Ensembl ID		ENSG00000152464	ENSG00000172336
Uniprot IDs		P78345	O75817
PDB IDs		6AHR 6AHU	6AHR 6AHU 6CWX 6LT7
Enriched GO Terms of Interacting Partners?		Ribonuclease P RNA Binding Multimeric Ribonuclease P Complex Ribonuclease P Activity TRNA 5'-leader Removal TRNA 5'-end Processing Ribonuclease MRP Complex TRNA Processing Nucleolar Ribonuclease P Complex TRNA Metabolic Process RNA Processing Ribonuclease P Complex Nucleolus RNA Metabolic Process RNA Binding RRNA Processing RRNA Metabolic Process Nucleic Acid Metabolic Process Endoribonuclease Complex Nucleoplasm Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Nucleus Negative Regulation Of Synaptic Vesicle Clustering Ribonuclease MRP Activity Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Phosphatidylinositol Phosphate Phosphatase Activity Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Peptidyl-serine Phosphorylation Postsynaptic Density Assembly Neuron-neuron Synaptic Transmission Negative Regulation Of Cell Size Anaphase-promoting Complex Binding Forebrain Morphogenesis Presynaptic Membrane Assembly Presynaptic Membrane Organization Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Postsynaptic Specialization Assembly Schmidt-Lanterman Incisure Negative Regulation Of Excitatory Postsynaptic Potential TRNA Decay Locomotor Rhythm Cellular Response To Electrical Stimulus	Ribonuclease MRP Complex TRNA Processing TRNA 5'-leader Removal TRNA 5'-end Processing TRNA Metabolic Process Ribonuclease P RNA Binding Multimeric Ribonuclease P Complex Ribonuclease P Activity RNA Processing Main Axon RNA Metabolic Process Nucleolar Ribonuclease P Complex Nucleus Regulation Of Interleukin-1 Beta Production Positive Regulation Of Endothelial Cell Migration Regulation Of Interleukin-1 Production Nucleic Acid Metabolic Process Perikaryon Cellular Response To Vascular Endothelial Growth Factor Stimulus RNA Binding Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Endothelial Cell Migration Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Toll-like Receptor Signaling Pathway Positive Regulation Of Cell Migration Positive Regulation Of Nitric Oxide Metabolic Process RRNA Processing Regulation Of Phosphorus Metabolic Process Postsynapse Response To Nerve Growth Factor Positive Regulation Of Cell Motility Cellular Response To Nerve Growth Factor Stimulus Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Locomotion RRNA Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of TRNA Methylation Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Protein Kinase C Signaling Ribonuclease MRP Activity Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Interleukin-1 Beta Production Macrophage Activation
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