PITRM1 and S100A7

		PITRM1	S100A7
Description		pitrilysin metallopeptidase 1	S100 calcium binding protein A7
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Extracellular Region Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Focal Adhesion Extracellular Matrix Azurophil Granule Lumen
	Molecular Function	Metalloendopeptidase Activity Protein Binding Enzyme Activator Activity Peptidase Activity Metallopeptidase Activity Zinc Ion Binding Hydrolase Activity Metal Ion Binding	Calcium Ion Binding Protein Binding Zinc Ion Binding Metal Ion Binding Transition Metal Ion Binding Calcium-dependent Protein Binding RAGE Receptor Binding Zinc Ion Sequestering Activity
	Biological Process	Proteolysis Protein Targeting To Mitochondrion Protein Processing	Response To Reactive Oxygen Species Angiogenesis Epidermis Development Positive Regulation Of T Cell Chemotaxis Keratinocyte Differentiation Response To Lipopolysaccharide Endothelial Cell Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Granulocyte Chemotaxis Positive Regulation Of Monocyte Chemotaxis
Pathways		Mitochondrial protein import	Neutrophil degranulation Metal sequestration by antimicrobial proteins
Drugs			Ibuprofen Zinc 8-anilinonaphthalene-1-sulfonic acid Dexibuprofen Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Metabolite levels ( 23823483) Scalp hair shape ( 26926045)	Blood protein levels ( 30072576)
Interacting Genes			9 interacting genes: CLVS2 COPS5 EGFR FABP5 RANBP9 S100A7L2 TGM2 UCHL5 WEE2-AS1
Entrez ID		10531	6278
HPRD ID		07142	02645
Ensembl ID		ENSG00000107959	ENSG00000143556
Uniprot IDs		A0A0A0MRX9 A0A7I2V397 Q5JRX3	P31151
PDB IDs		4L3T 4NGE 4RPU 6XOS 6XOT 6XOU 6XOV 6XOW	1PSR 2PSR 2WND 2WOR 2WOS 3PSR 4AQJ
Enriched GO Terms of Interacting Partners?		Protein Targeting To Mitochondrion	Multivesicular Body, Internal Vesicle Lumen Peptide Dopaminyltransferase Activity Histone Serotonyltransferase Activity Peptide Histaminyltransferase Activity Protein-glutamine Glutaminase Activity Peptide Noradrenalinyltransferase Activity Peptidase Activity Peptide Serotonyltransferase Activity Histone Dopaminyltransferase Activity Lysosome Organization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?