IFITM3 and LYPD5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		IFITM3	LYPD5
Description		interferon induced transmembrane protein 3	LY6/PLAUR domain containing 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Endosome Plasma Membrane Membrane Early Endosome Membrane Late Endosome Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm	Extracellular Region Plasma Membrane Membrane Side Of Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Immune System Process Immune Response Response To Virus Negative Regulation Of Viral Transcription Response To Type II Interferon Response To Interferon-alpha Response To Interferon-beta Negative Regulation Of Viral Genome Replication Innate Immune Response Host-mediated Suppression Of Symbiont Invasion Defense Response To Virus Type I Interferon-mediated Signaling Pathway
Pathways		Interferon alpha/beta signaling	Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Eosinophil count ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Multiple sclerosis ( 31604244) Neutrophil percentage of granulocytes ( 27863252)	Breast cancer ( 23535729 29059683) Reading or mathematical ability ( 25003214)
Interacting Genes		26 interacting genes: ABHD16A AQP6 CD53 ELOVL2 ERGIC3 FAM210B FFAR2 FKBP7 GLP1R GPR37 GPRC5D KIR2DL3 LYPD5 MS4A3 NEDD4 OPRM1 PLP1 PTAFR REEP4 SGPL1 SLC10A1 SLC10A2 SLC16A7 TMEM14B TMEM86B VKORC1	8 interacting genes: BET1 EHHADH ERG28 ERMP1 IFITM3 NINJ2 PLPPR2 TSPO
Entrez ID		10410	284348
HPRD ID		05719	08084
Ensembl ID		ENSG00000142089	ENSG00000159871
Uniprot IDs		Q01628	Q6UWN5
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane G Protein-coupled Receptor Activity G Protein-coupled Peptide Receptor Activity Bile Acid:sodium Symporter Activity Endoplasmic Reticulum
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