B3GALT5 and DEFB103A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		B3GALT5	DEFB103A
Description		beta-1,3-galactosyltransferase 5	defensin beta 103A
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Membrane	Extracellular Region Extracellular Space Golgi Lumen
	Molecular Function	Protein Binding N-acetyl-beta-D-glucosaminide Beta-(1,3)-galactosyltransferase Activity Transferase Activity Glycosyltransferase Activity Hexosyltransferase Activity	Protein Binding CCR6 Chemokine Receptor Binding Chemoattractant Activity
	Biological Process	Protein Glycosylation Protein O-linked Glycosylation Lipid Metabolic Process Oligosaccharide Biosynthetic Process Response To Bacterium Carbohydrate Derivative Biosynthetic Process	Defense Response Killing Of Cells Of Another Organism Defense Response To Bacterium Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Positive Chemotaxis Killing By Host Of Symbiont Cells Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Defense Response To Symbiont
Pathways		Lewis blood group biosynthesis	Beta defensins Defensins
Drugs
Diseases
GWAS		Alcohol dependence ( 26365420) Corneal astigmatism ( 29422769) Metabolite levels ( 23823483) Obsessive-compulsive symptoms ( 26859814) Suicide risk ( 21041247)
Interacting Genes		3 interacting genes: CLEC2D DEFB103A DEFB103B	11 interacting genes: AQP6 B3GALT5 EBP ERGIC3 ODF4 SCN3B SPATA31A7 SSMEM1 TMEM14B TMEM31 TMPRSS2
Entrez ID		10317	414325
HPRD ID		06818	19320
Ensembl ID		ENSG00000183778	ENSG00000176797
Uniprot IDs		A0A0A0MS93 Q9Y2C3	A0A894JZ42 P81534
PDB IDs			1KJ6
Enriched GO Terms of Interacting Partners?		CCR6 Chemokine Receptor Binding Preribosome, Small Subunit Precursor Chemoattractant Activity Killing By Host Of Symbiont Cells Biological Process Involved In Interaction With Symbiont Positive Chemotaxis Defense Response To Gram-negative Bacterium ABC-type Sterol Transporter Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Golgi Lumen Killing Of Cells Of Another Organism Defense Response To Gram-positive Bacterium Glycoprotein Transport Cellular Response To High Density Lipoprotein Particle Stimulus Antimicrobial Humoral Response Floppase Activity Cell Killing RRNA Processing Phosphatidylcholine Floppase Activity Cell Chemotaxis Toxin Transmembrane Transporter Activity Granular Component RRNA Metabolic Process Humoral Immune Response Negative Regulation Of Cholesterol Storage Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane Xenobiotic Export From Cell Low-density Lipoprotein Particle Remodeling Phospholipid Homeostasis Phospholipid Efflux Amyloid Precursor Protein Catabolic Process Reverse Cholesterol Transport External Side Of Plasma Membrane Negative Regulation Of Macrophage Derived Foam Cell Differentiation Response To Other Organism Negative Regulation Of GTPase Activity Locomotion Defense Response To Bacterium Chemotaxis Host-mediated Activation Of Viral Transcription Positive Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Amyloid-beta Formation Negative Regulation Of Lipid Storage Intracellular Cholesterol Transport High-density Lipoprotein Particle Remodeling Response To External Biotic Stimulus Response To Bacterium Intracellular Sterol Transport Cholesterol Transfer Activity Amyloid Precursor Protein Metabolic Process	Membrane PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport C-8 Sterol Isomerase Activity Cholesterol-5,6-oxide Hydrolase Activity Cholestenol Delta-isomerase Activity Retrograde Transporter Complex, Golgi To ER Entry Receptor-mediated Virion Attachment To Host Cell Cholesterol Biosynthetic Process Via Lathosterol Cholesterol Biosynthetic Process Via Desmosterol Steroid Delta-isomerase Activity Viral Translation Transporter Complex Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport
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