TIMM17B and TIMM23

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		TIMM17B	TIMM23
Description		translocase of inner mitochondrial membrane 17B	translocase of inner mitochondrial membrane 23
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Membrane	Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Mitochondrial Intermembrane Space Membrane
	Molecular Function	Protein Binding Protein Transmembrane Transporter Activity	Protein Binding Protein Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process	Protein Targeting To Mitochondrion Intracellular Protein Transport Protein Transport Protein Import Into Mitochondrial Matrix	Protein Targeting To Mitochondrion Intracellular Protein Transport Protein Transport Protein Import Into Mitochondrial Matrix Type 2 Mitophagy
Pathways		Mitochondrial protein import Mitochondrial protein import	Mitochondrial protein import Mitochondrial protein import
Drugs
Diseases
GWAS		Type 2 diabetes ( 30718926)	Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis ( 30926877) Mean corpuscular hemoglobin ( 20139978) Mean corpuscular volume ( 20139978) Prostate cancer ( 25939597 27262462)
Interacting Genes		9 interacting genes: APP CIDEB CREB3 MPC2 RHBDD2 TEX44 TIMM23 TRIM55 TRIM63	17 interacting genes: AQP6 CREB3L1 EBP FAM210B FXYD3 GOLT1A HSD17B13 JAGN1 RNASEK SCN3B SLC16A7 TIMM17B TLCD4 TMEM14B TMEM86B TMEM88 TSPAN8
Entrez ID		10245	100287932
HPRD ID		02218
Ensembl ID		ENSG00000126768	ENSG00000265354
Uniprot IDs		O60830	O14925
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Intracellular Transport Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Response To Stress Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Monocyte Chemotaxis Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Deacetylase Activity Arginyl-tRNA--protein Transferase Activity Acetylcholine Receptor Activator Activity Response To Interleukin-1 Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Cellular Localization Lipoprotein Particle Positive Regulation Of Protein Import Establishment Of Localization In Cell Protein Arginylation Protein K63-linked Ubiquitination Pyruvate Import Into Mitochondria Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Mononuclear Cell Migration Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Leukocyte Chemotaxis Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Mitochondrial Inner Membrane Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Identical Protein Binding Intracellular Signal Transduction Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Pyruvate Transmembrane Transporter Activity	Membrane
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