TIMM17B and TEX44

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TIMM17B	TEX44
Description		translocase of inner mitochondrial membrane 17B	testis expressed 44
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Membrane	Cytoplasm
	Molecular Function	Protein Binding Protein Transmembrane Transporter Activity	Protein Binding
	Biological Process	Protein Targeting To Mitochondrion Intracellular Protein Transport Protein Transport Protein Import Into Mitochondrial Matrix
Pathways		Mitochondrial protein import Mitochondrial protein import
Drugs
Diseases
GWAS		Type 2 diabetes ( 30718926)	Femur bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		9 interacting genes: APP CIDEB CREB3 MPC2 RHBDD2 TEX44 TIMM23 TRIM55 TRIM63	13 interacting genes: APOC1 APP C3orf33 CIDEB COX20 CPT1B DERL1 MICOS13 MPC2 RHBDD2 SYPL1 TIMM17B TMEM14B
Entrez ID		10245	165100
HPRD ID		02218	14602
Ensembl ID		ENSG00000126768	ENSG00000177673
Uniprot IDs		O60830	Q53QW1
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Intracellular Transport Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Response To Stress Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Monocyte Chemotaxis Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Deacetylase Activity Arginyl-tRNA--protein Transferase Activity Acetylcholine Receptor Activator Activity Response To Interleukin-1 Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Cellular Localization Lipoprotein Particle Positive Regulation Of Protein Import Establishment Of Localization In Cell Protein Arginylation Protein K63-linked Ubiquitination Pyruvate Import Into Mitochondria Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Mononuclear Cell Migration Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Leukocyte Chemotaxis Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Mitochondrial Inner Membrane Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Identical Protein Binding Intracellular Signal Transduction Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Pyruvate Transmembrane Transporter Activity	Mitochondrial Inner Membrane Signal Recognition Particle Binding Very-low-density Lipoprotein Particle Assembly High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Plasma Lipoprotein Particle Assembly Intracellular Transport Membrane Mitochondrion Mitochondrial Transmembrane Transport Protein-lipid Complex Assembly Lipoprotein Metabolic Process Mitochondrial Transport Regulation Of Triglyceride Metabolic Process Negative Regulation Of Phosphatidylcholine Catabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Localization Establishment Of Localization In Cell Endoplasmic Reticulum Unfolded Protein Response Lipid Transport Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Pyruvate Import Into Mitochondria Derlin-1-VIMP Complex Regulation Of Phosphatidylcholine Catabolic Process PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Carnitine O-palmitoyltransferase Activity ERAD Pathway Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation
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