CDH12 and CDH18

Number of citations of the paper that reports this interaction (PubMedID 10861224)
34

Data Source:
HPRD (in vitro, in vivo)

		CDH12	CDH18
Description		cadherin 12	cadherin 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Adherens Junction Membrane Catenin Complex	Plasma Membrane Adherens Junction Membrane Catenin Complex
	Molecular Function	Calcium Ion Binding Beta-catenin Binding Cadherin Binding Metal Ion Binding	Calcium Ion Binding Beta-catenin Binding Cadherin Binding Metal Ion Binding
	Biological Process	Cell Morphogenesis Cell-cell Junction Assembly Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Migration Adherens Junction Organization Cell-cell Adhesion Mediated By Cadherin Cell-cell Adhesion	Cell Morphogenesis Cell-cell Junction Assembly Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Migration Adherens Junction Organization Cell-cell Adhesion Mediated By Cadherin Cell-cell Adhesion
Pathways		Adherens junctions interactions	Adherens junctions interactions
Drugs
Diseases
GWAS		Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (physical activity interaction) ( 28448500) Brooding (response to stress) ( 30886212) Dimensional psychopathology (Cognitive) ( 29496196) Low white blood cell count (conditioned on rs2814778) ( 29596498) Mosquito bite size ( 28199695) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Waist circumference ( 19557197)	Childhood body mass index ( 33045005) Depression (quantitative trait) ( 20800221) Diabetes (gestational) ( 31269844) Erectile dysfunction ( 30583798) Metabolic coherence (transcriptomic) ( 30852652) Mitochondrial DNA levels ( 25240745) Obesity in adult survivors of childhood cancer exposed to cranial radiation ( 25963547) Obstetric antiphospholipid syndrome ( 28424481) Resistant hypertension ( 31545351) Response to anti-TNF therapy in rheumatoid arthritis ( 26776603) Serum metabolite concentrations in chronic kidney disease ( 29545352) Type 2 diabetes ( 31049640)
Interacting Genes		2 interacting genes: CDH18 CDH7	4 interacting genes: CDH12 CDH6 CDH9 MYOG
Entrez ID		1010	1016
HPRD ID		11081	04314
Ensembl ID		ENSG00000154162	ENSG00000145526
Uniprot IDs		P55289	D6RER2 Q13634
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell-cell Adhesion Mediated By Cadherin Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Catenin Complex Adherens Junction Organization Beta-catenin Binding Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell-cell Junction Assembly Cell-cell Junction Organization Cell Morphogenesis Adherens Junction Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell Junction Assembly Cadherin Binding Cell Junction Organization Cell-cell Adhesion Calcium Ion Binding Cell Adhesion Cell Migration Cell Motility Anatomical Structure Morphogenesis Cellular Component Assembly	Catenin Complex Cell-cell Adhesion Mediated By Cadherin Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization Beta-catenin Binding Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell-cell Junction Assembly Cell-cell Junction Organization Cell Morphogenesis Adherens Junction Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Synaptic Membrane Adhesion Cell Junction Assembly Cadherin Binding Cell Junction Organization Cell-cell Adhesion Calcium Ion Binding Positive Regulation Of Muscle Atrophy Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Cell Adhesion Cell Migration Cell Motility Response To Denervation Involved In Regulation Of Muscle Adaptation Striated Muscle Atrophy Response To Muscle Inactivity Positive Regulation Of Skeletal Muscle Fiber Development Muscle Atrophy CAMP Biosynthetic Process Adenylate Cyclase Activity Regulation Of Skeletal Muscle Fiber Development Response To Inactivity Adenylate Cyclase Binding Regulation Of Skeletal Muscle Satellite Cell Proliferation Cellular Response To Forskolin Positive Regulation Of Myotube Differentiation Muscle Cell Fate Commitment Regulation Of Skeletal Muscle Cell Proliferation Cellular Response To Lithium Ion Response To Forskolin Response To Lithium Ion Phosphorus-oxygen Lyase Activity Anatomical Structure Morphogenesis Positive Regulation Of Skeletal Muscle Tissue Development CAMP Metabolic Process Cyclic Nucleotide Biosynthetic Process Cellular Response To Lipid Positive Regulation Of Striated Muscle Tissue Development Regulation Of Myoblast Fusion Myotube Differentiation
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