CDH12 and CDH7

Number of citations of the paper that reports this interaction (PubMedID 10861224)
34

Data Source:
HPRD (in vivo)

		CDH12	CDH7
Description		cadherin 12	cadherin 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Adherens Junction Membrane Catenin Complex	Plasma Membrane Adherens Junction Membrane Catenin Complex
	Molecular Function	Calcium Ion Binding Beta-catenin Binding Cadherin Binding Metal Ion Binding	Calcium Ion Binding Beta-catenin Binding Cadherin Binding Metal Ion Binding
	Biological Process	Cell Morphogenesis Cell-cell Junction Assembly Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Migration Adherens Junction Organization Cell-cell Adhesion Mediated By Cadherin Cell-cell Adhesion	Cell Morphogenesis Cell-cell Junction Assembly Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Migration Adherens Junction Organization Cell-cell Adhesion Mediated By Cadherin Cell-cell Adhesion
Pathways		Adherens junctions interactions	Adherens junctions interactions
Drugs
Diseases
GWAS		Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (physical activity interaction) ( 28448500) Brooding (response to stress) ( 30886212) Dimensional psychopathology (Cognitive) ( 29496196) Low white blood cell count (conditioned on rs2814778) ( 29596498) Mosquito bite size ( 28199695) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Waist circumference ( 19557197)	Adult body size ( 32376654) Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) ( 24025145) Body mass index ( 28892062) Cardiac Troponin-T levels ( 23247143) Fractional excretion of metabolites in chronic kidney disease ( 29545352) Glucagon levels in response to oral glucose tolerance test (decremental area under the curve for 0-30 minutes) ( 33407418) Irritable mood ( 29500382) Metabolite levels ( 23823483) Prudent dietary pattern ( 28644415)
Interacting Genes		2 interacting genes: CDH18 CDH7	6 interacting genes: CDH12 CDH15 CDH6 CDH9 CTNNB1 FGF21
Entrez ID		1010	1005
HPRD ID		11081	12049
Ensembl ID		ENSG00000154162	ENSG00000081138
Uniprot IDs		P55289	F5H5X9 Q8IY78 Q9ULB5
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell-cell Adhesion Mediated By Cadherin Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Catenin Complex Adherens Junction Organization Beta-catenin Binding Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell-cell Junction Assembly Cell-cell Junction Organization Cell Morphogenesis Adherens Junction Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell Junction Assembly Cadherin Binding Cell Junction Organization Cell-cell Adhesion Calcium Ion Binding Cell Adhesion Cell Migration Cell Motility Anatomical Structure Morphogenesis Cellular Component Assembly	Catenin Complex Cell-cell Adhesion Mediated By Cadherin Adherens Junction Organization Cell-cell Junction Assembly Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell-cell Junction Organization Cell Morphogenesis Adherens Junction Cell Junction Assembly Cadherin Binding Beta-catenin Binding Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell Junction Organization Cell-cell Adhesion Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell Adhesion Cell Migration Cell Motility Calcium Ion Binding Anatomical Structure Morphogenesis Synaptic Membrane Adhesion Fibroblast Growth Factor Receptor Signaling Pathway Cellular Component Assembly Glial Cell Fate Determination Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Developmental Process Mesenchymal Stem Cell Differentiation Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic Beta-catenin-ICAT Complex Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Renal Inner Medulla Development Scrib-APC-beta-catenin Complex Renal Outer Medulla Development Renal Vesicle Formation Positive Regulation Of Branching Involved In Lung Morphogenesis Neural Plate Development Oviduct Development Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Fungiform Papilla Formation Beta-catenin-TCF7L2 Complex Astrocyte-dopaminergic Neuron Signaling Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Regulation Of Centriole-centriole Cohesion Embryonic Skeletal Limb Joint Morphogenesis Lung Induction Catenin-TCF7L2 Complex Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Negative Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Acinar Cell Differentiation
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