PTGES3L-AARSD1 and TRIM45

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PTGES3L-AARSD1	TRIM45
Description		PTGES3L-AARSD1 readthrough	tripartite motif containing 45
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Cytosol Intercellular Bridge
	Molecular Function		Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process		Inflammatory Response Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Inflammatory Response Bone Development Protein K48-linked Ubiquitination
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS
Interacting Genes		8 interacting genes: ARID4B DYNLT1 ERBB2 FAAP100 SPANXN3 TRIM45 ZMYND19 ZNF185	18 interacting genes: CDC42 GABARAPL2 MED10 MEOX2 PTGES3L-AARSD1 TAB2 TAX1BP1 TEPSIN TFIP11 UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 ZMYND19
Entrez ID		100885850	80263
HPRD ID			15562
Ensembl ID		ENSG00000108825	ENSG00000134253
Uniprot IDs			Q9H8W5
PDB IDs			2DS4
Enriched GO Terms of Interacting Partners?			Ubiquitin Conjugating Enzyme Activity Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Ubiquitin-protein Transferase Activity Protein K11-linked Ubiquitination Protein K63-linked Ubiquitination Protein Modification Process Protein Monoubiquitination ISG15 Transferase Activity Ubiquitin-dependent Protein Catabolic Process ISG15-protein Conjugation Modification-dependent Protein Catabolic Process Nucleotide Binding Ubiquitin Protein Ligase Activity Protein Metabolic Process ATP Binding Proteolysis Involved In Protein Catabolic Process Protein Autoubiquitination Transferase Activity Protein K6-linked Ubiquitination Catabolic Process Macromolecule Catabolic Process Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Proteolysis Coated Vesicle Membrane GBD Domain Binding Storage Vacuole Positive Regulation Of Reciprocal Meiotic Recombination Protein Localization To Phagocytic Vesicle Spliceosomal Complex Disassembly Negative Regulation Of BMP Signaling Pathway Positive Regulation Of Cell Cycle Process Negative Regulation Of Macromolecule Metabolic Process
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