USP2-AS1 and PEX2

Number of citations of the paper that reports this interaction (PubMedID 36359803)
47

Data Source:
BioGRID (unspecified method)

		USP2-AS1	PEX2
Description		USP2 antisense RNA 1	peroxisomal biogenesis factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Peroxisome Peroxisomal Membrane Cytosol Membrane Cdc73/Paf1 Complex
	Molecular Function		Protein Binding Zinc Ion Binding Protein Transmembrane Transporter Activity Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process		Very Long-chain Fatty Acid Metabolic Process Pexophagy Protein Monoubiquitination Fatty Acid Beta-oxidation Peroxisome Organization Protein Transport Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Receptor Recycling Protein Ubiquitination Protein Destabilization Cellular Response To Reactive Oxygen Species Protein Unfolding Protein Import Into Peroxisome Matrix, Substrate Release Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Epithelial Cell Proliferation Response To Amino Acid Starvation
Pathways			E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import
Drugs
Diseases			Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Bitter alcoholic beverage consumption ( 31046077) Estimated glomerular filtration rate ( 31152163) Femur bone mineral density x serum urate levels interaction ( 34046847) Parental longevity (both parents in top 10%) ( 29227965)	Fasting plasma glucose ( 31170924) Height ( 20881960 31562340) Infant length ( 25281659) Menarche (age at onset) ( 25231870 27182965) Nicotine dependence ( 28440896) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
Interacting Genes		15 interacting genes: ARIH2 ATR COX15 CTSC DCAF13 ENO2 FAAH2 PCBD2 PEX2 PUS1 RPSA SPRR4 STX10 TP53I3 TSC1	5 interacting genes: APP ERG28 PEX10 TLE1 USP2-AS1
Entrez ID		100499227	5828
HPRD ID			01367
Ensembl ID		ENSG00000245248	ENSG00000164751
Uniprot IDs			P28328
PDB IDs
Enriched GO Terms of Interacting Partners?			Acetylcholine Receptor Activator Activity Negative Regulation Of Canonical Wnt Signaling Pathway Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Negative Regulation Of Wnt Signaling Pathway Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Target-directed MiRNA Degradation Elongin Complex Transport Vesicle Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Protein Import Into Peroxisome Matrix, Substrate Release Axon Choice Point Recognition Early Endosome Membrane
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