GOLGA8F and ERP27

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GOLGA8F	ERP27
Description		golgin A8 family member F	endoplasmic reticulum protein 27
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cis-Golgi Network	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function		Protein Disulfide Isomerase Activity Protein Binding
	Biological Process		Protein Folding Response To Unfolded Protein Response To Endoplasmic Reticulum Stress
Pathways
Drugs
Diseases
GWAS			Finger osteoarthritis severity (hand Klsum) ( 33055079) Hand grip strength ( 29313844) Hand osteoarthritis severity (hand Klsum) ( 33055079) Low hand grip strength (60 years and older) (EWGSOP) ( 33510174) Osteoarthritis of the hand ( 28855172)
Interacting Genes		20 interacting genes: ATF4 BAAT BEX3 BEX5 CDC5L ERP27 GOSR2 HDDC3 KCTD6 MEOX2 MRFAP1 PDE4D PDE4DIP PPP2R1A SPAG5 SSX2IP STX11 TCF4 USHBP1 ZNF471	10 interacting genes: BLOC1S2 C12orf60 GOLGA8F MED20 PDIA3 SGTA UBL4A UBQLN1 UBQLN2 UBQLN4
Entrez ID		100132565	121506
HPRD ID			08723
Ensembl ID		ENSG00000153684	ENSG00000139055
Uniprot IDs		A0A0G2JP71 P0DX52	F5GYS6 Q96DN0
PDB IDs			2L4C 4F9Z
Enriched GO Terms of Interacting Partners?			Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Polyubiquitin Modification-dependent Protein Binding Regulation Of Proteasomal Protein Catabolic Process Response To Endoplasmic Reticulum Stress Autophagosome Regulation Of Response To Endoplasmic Reticulum Stress Post-translational Protein Targeting To Endoplasmic Reticulum Membrane ERAD Pathway Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Regulation Of Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Targeting To ER Protein Insertion Into ER Membrane Macromolecule Catabolic Process Regulation Of Cellular Response To Stress Establishment Of Protein Localization To Endoplasmic Reticulum Regulation Of Macroautophagy Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Autophagy Negative Regulation Of Store-operated Calcium Channel Activity Protein Targeting To Membrane Protein Insertion Into Membrane Cellular Response To Stress Tapasin-ERp57 Complex TRC Complex Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of Autophagy Nuclear Proteasome Complex Autophagosome Assembly Autophagosome Organization BAT3 Complex Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Autophagosome Maturation Identical Protein Binding Extrinsic Apoptotic Signaling Pathway Proteasomal Protein Catabolic Process BAT3 Complex Binding Negative Regulation Of Clathrin-dependent Endocytosis Catabolic Process Cytosolic Proteasome Complex Positive Regulation Of Catabolic Process
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