HELZ

Description		helicase with zinc finger
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Membrane P Granule
	Molecular Function	Nucleotide Binding RNA Binding Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Pathways
Drugs
Diseases
GWAS		Lymphocyte count ( 32888494) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) Putamen volume ( 29147026) Visceral fat ( 30942860)
Interacting Genes		4 interacting genes: GRB2 SH3YL1 SMYD3 STAT5A
Entrez ID		9931
HPRD ID		10452
Ensembl ID		ENSG00000198265
Uniprot IDs		A0A2P0H7U5 B7ZLW2 J3QS41 P42694
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Natural Killer Cell Mediated Immunity Natural Killer Cell Mediated Immunity Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Cytotoxicity Leukocyte Mediated Cytotoxicity Guanyl-nucleotide Exchange Factor Adaptor Activity Regulation Of Leukocyte Mediated Cytotoxicity Lymphocyte Mediated Immunity Leukocyte Mediated Immunity Grb2-EGFR Complex Positive Regulation Of Mast Cell Differentiation Cell Development Positive Regulation Of Lymphocyte Activation Positive Regulation Of Cell-cell Adhesion Negative Regulation Of Immune Response Positive Regulation Of T Cell Activation Positive Regulation Of Leukocyte Cell-cell Adhesion Cell Killing Morphogenesis Of An Epithelium Branching Involved In Labyrinthine Layer Morphogenesis Regulation Of Lymphocyte Mediated Immunity T Cell Activation Neurotrophin TRKA Receptor Binding Positive Regulation Of Gamma-delta T Cell Differentiation Regulation Of Mast Cell Differentiation Interleukin-4-mediated Signaling Pathway Taurine Metabolic Process Epithelial Cell Differentiation Involved In Prostate Gland Development Development Of Secondary Female Sexual Characteristics Thrombopoietin-mediated Signaling Pathway Negative Regulation Of T-helper 17 Cell Lineage Commitment Negative Regulation Of Mast Cell Apoptotic Process Eosinophil Differentiation Mucosa-associated Lymphoid Tissue Development Interleukin-9-mediated Signaling Pathway Peyer's Patch Development Luteinization Positive Regulation Of Mast Cell Proliferation Negative Regulation Of Erythrocyte Differentiation Interleukin-3-mediated Signaling Pathway Regulation Of Mast Cell Apoptotic Process Interleukin-7-mediated Signaling Pathway Activated T Cell Proliferation Positive Regulation Of Natural Killer Cell Differentiation Interleukin-5-mediated Signaling Pathway Mast Cell Apoptotic Process Regulation Of Mast Cell Proliferation Interleukin-15-mediated Signaling Pathway Mast Cell Differentiation Development Of Secondary Sexual Characteristics
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