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SNX17
Description
sorting nexin 17
Image
GO Annotations
Cellular Component
Cytoplasm
Endosome
Early Endosome
Golgi Apparatus
Cytosol
Endosome Membrane
Membrane
Cytoplasmic Vesicle Membrane
Cytoplasmic Vesicle
Protein-containing Complex
Molecular Function
Signaling Receptor Binding
Protein Binding
Lipid Binding
Phosphatidylinositol Binding
Low-density Lipoprotein Particle Receptor Binding
Biological Process
Kidney Development
Cardiac Septum Development
Cholesterol Catabolic Process
Intracellular Protein Transport
Receptor-mediated Endocytosis
Signal Transduction
Protein Transport
Vesicle-mediated Transport
Endosomal Transport
Regulation Of Endocytosis
Endocytic Recycling
Aorta Development
Coronary Vasculature Development
Pathways
Drugs
Diseases
GWAS
Alcohol use disorder (total score) (
30336701
)
Crohn's disease (
28067908
)
High light scatter reticulocyte count (
27863252
)
Inflammatory bowel disease (
28067908
)
LDL cholesterol levels in current drinkers (
30698716
)
LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) (
30698716
)
LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) (
30698716
)
Microalbuminuria (
31511532
)
Non-oily fish consumption (
32066663
)
Refractive error (
32231278
)
Reticulocyte count (
27863252
)
Reticulocyte fraction of red cells (
27863252
)
Serum alkaline phosphatase levels (
33339817
)
Triglyceride levels (
34074324
32902719
32203549
30698716
)
Triglyceride levels in current drinkers (
30698716
)
Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) (
30698716
)
Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) (
30698716
)
Urinary albumin excretion (
30220432
)
Urinary albumin excretion (no hypertensive medication) (
30220432
)
Urinary albumin-to-creatinine ratio (
30910378
31511532
31630189
32600054
)
Urinary sodium to potassium ratio (
30910378
)
Novel Interacting Genes
3 novel interacting genes:
KCNG3
PEX10
RHOB
Interacting Genes
16 interacting genes:
ACE2
ANXA2
APP
HOXC8
HRAS
LDLR
LRP1
LRP2
LRP8
RABAC1
RIN1
RLIM
RNF128
SELP
SKIL
VLDLR
Entrez ID
9784
HPRD ID
05812
Ensembl ID
ENSG00000115234
Uniprot IDs
B4DDM3
B4DQ37
B4DTB8
Q15036
PDB IDs
3FOG
3LUI
4GXB
4TKN
7RM8
9AU7
Enriched GO Terms of Interacting Partners
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Low-density Lipoprotein Particle Receptor Activity
Positive Regulation Of Protein Catabolic Process In The Vacuole
Endocytosis
Apolipoprotein Binding
Very-low-density Lipoprotein Particle Receptor Activity
Import Into Cell
Clathrin-coated Pit
Positive Regulation Of Lysosomal Protein Catabolic Process
Cargo Receptor Activity
Receptor Complex
Vesicle-mediated Transport
Regulation Of Lysosomal Protein Catabolic Process
Retinoid Metabolic Process
Receptor-mediated Endocytosis
Reelin Receptor Activity
Diterpenoid Metabolic Process
Calcium-dependent Protein Binding
Regulation Of Protein Catabolic Process
Calcium Ion Binding
Positive Regulation Of Multicellular Organismal Process
Positive Regulation Of Protein Catabolic Process
Terpenoid Metabolic Process
Amyloid-beta Clearance
Isoprenoid Metabolic Process
Astrocyte Activation Involved In Immune Response
Anatomical Structure Morphogenesis
Regulation Of Multicellular Organismal Process
Positive Regulation Of Cellular Component Organization
Regulation Of Cellular Component Organization
Early Endosome
Plasma Membrane
Amyloid-beta Clearance By Cellular Catabolic Process
Ventral Spinal Cord Development
Regulation Of Neurogenesis
Artery Morphogenesis
Clathrin Heavy Chain Binding
Reelin-mediated Signaling Pathway
Regulation Of Nervous System Development
Membrane
Plasma Membrane Protein Complex
Low-density Lipoprotein Particle
Amyloid-beta Binding
Positive Regulation Of Dendrite Development
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Protein Metabolic Process
Heparan Sulfate Proteoglycan Binding
Regulation Of Amyloid Fibril Formation
Astrocyte Activation
Neuron Projection Morphogenesis
Regulation Of Low-density Lipoprotein Particle Clearance
Tagcloud
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