ESPL1

Gene Name		extra spindle pole bodies homolog 1 (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Centrosome Cytosol
	Molecular Function	Catalytic Activity Protein Binding Cysteine-type Peptidase Activity
	Biological Process	Mitotic Sister Chromatid Segregation Meiotic Spindle Organization Mitotic Cell Cycle Cytokinesis Proteolysis Apoptotic Process Establishment Of Mitotic Spindle Localization Homologous Chromosome Segregation Positive Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Sister Chromatid Cohesion
Pathways		Separation of Sister Chromatids Mitotic Anaphase Cell Cycle, Mitotic M Phase Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: PJA1 RFFL TRIM55 TRIM63 USP21 USP28
Entrez ID		9700
HPRD ID		06825
Ensembl ID		ENSG00000135476
Uniprot IDs		Q14674
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Catabolic Process Cellular Macromolecule Catabolic Process Proteolysis Cellular Protein Modification Process Protein Ubiquitination Protein Deubiquitination Protein Modification By Small Protein Conjugation Protein Modification By Small Protein Removal Regulation Of Proteolysis Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of Proteasomal Protein Catabolic Process Cellular Protein Metabolic Process Skeletal Muscle Atrophy Striated Muscle Atrophy Muscle Atrophy Negative Regulation Of Execution Phase Of Apoptosis Skeletal Muscle Adaptation Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Protein Metabolic Process Regulation Of Protein Catabolic Process Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Protein K48-linked Deubiquitination Protein K63-linked Deubiquitination Histone Deubiquitination Negative Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Execution Phase Of Apoptosis Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Cellular Response To Dexamethasone Stimulus Regulation Of Fibroblast Migration Response To Dexamethasone Regulation Of Cellular Protein Metabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Cytokine-mediated Signaling Pathway Negative Regulation Of Response To Cytokine Stimulus Response To Electrical Stimulus Regulation Of Signal Transduction By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Protein Metabolic Process Cellular Response To Glucocorticoid Stimulus Cellular Response To Corticosteroid Stimulus
Tagcloud ?		12q13 1p36 ankrd11 cdls cleaves cohesin cornelia deeper discriminating encompassing exome filtering hdac8 intellectual intronic kbg lange merits mosaic multisystem nipbl novo partitioning rad21 recursive separase smc1a smc3 undetected