SOCS5

Gene Name		suppressor of cytokine signaling 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm
	Molecular Function	Protein Kinase Inhibitor Activity Epidermal Growth Factor Receptor Binding Protein Binding Receptor Tyrosine Kinase Binding
	Biological Process	Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity JAK-STAT Cascade Negative Regulation Of Signal Transduction Cell Growth Protein Ubiquitination Cytokine-mediated Signaling Pathway Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Growth Positive Regulation Of T-helper 1 Cell Differentiation Negative Regulation Of T-helper 2 Cell Differentiation Negative Regulation Of JAK-STAT Cascade
Pathways
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 21685187) Height ( 20881960)
Protein-protein Interactions		7 interactors: APP CASP3 EGFR IL4R KIT TMBIM1 UBC
Entrez ID		9655
HPRD ID		06159
Ensembl ID		ENSG00000171150
Uniprot IDs		O75159
PDB IDs
Enriched GO Terms of Interacting Partners?		Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Response To Light Stimulus Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Regulation Of Protein Phosphorylation Immune System Process Response To Abiotic Stimulus Response To Radiation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Protein Metabolic Process Immune Response Regulation Of Immune System Process Regulation Of Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway Defense Response ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Response To Growth Factor Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Phosphorus Metabolic Process Response To Fibroblast Growth Factor Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Catalytic Activity Regulation Of Cell Death Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of MAP Kinase Activity Response To Cytokine Fc-epsilon Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Negative Regulation Of Catalytic Activity Innate Immune Response Learning Or Memory Fc Receptor Signaling Pathway Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Intracellular Signal Transduction Cellular Response To Organic Substance Regulation Of Immune Response Positive Regulation Of Cell Cycle Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Stress Cognition
Tagcloud ?		actionable adenocarcinomas akt1 alk braf capture ccdc6 cd74 clip4 deemed driver fusions g719a genomic introns kif5b map2k1 nccn ngs nras pack pik3ca profiling rearranged ret ros1 targetable uniform v600e