FADS2

Gene Name		fatty acid desaturase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Stearoyl-CoA 9-desaturase Activity Iron Ion Binding Heme Binding
	Biological Process	Unsaturated Fatty Acid Biosynthetic Process Unsaturated Fatty Acid Metabolic Process Alpha-linolenic Acid Metabolic Process Linoleic Acid Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways		Metabolism of lipids and lipoproteins alpha-linolenic acid (ALA) metabolism alpha-linolenic (omega3) and linoleic (omega6) acid metabolism Linoleic acid (LA) metabolism
Drugs
Diseases
GWAS		Cholesterol, total ( 19060911 20686565) Comprehensive strength and appendicular lean mass ( 22960237) HDL cholesterol ( 19060906 19060911 20686565) Inflammatory bowel disease ( 23128233) LDL cholesterol ( 19060910 19060911 20686565) Lipid metabolism phenotypes ( 22286219) Liver enzyme levels (alkaline phosphatase) ( 22001757) Metabolic syndrome ( 20694148) Metabolite levels ( 23378610 22916037) Oleic acid (18:1n-9) plasma levels ( 23362303) Palmitoleic acid (16:1n-7) plasma levels ( 23362303) Phospholipid levels (plasma) ( 21829377 22359512) Response to statin therapy ( 20339536) Sphingolipid levels ( 22359512) Stearic acid (18:0) plasma levels ( 23362303) Triglycerides ( 19060906 20686565)
Protein-protein Interactions		1 interactors: ATXN1L
Entrez ID		9415
HPRD ID		05854
Ensembl ID		ENSG00000134824
Uniprot IDs		B7Z634 O95864
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of Hematopoietic Stem Cell Proliferation
Tagcloud ?		aberrations acly biphasic cascade chemoprevention citrate desaturase disturbed fatty harboring hbv hcc hepatocytes lipid livers lyase metabolism mtor pre remarkably srebf1 starting sterol subsided synchronized transgenic tumorigenesis upregulate