TTYH2

Name	tweety family member 2
Structure
Interactors	15 interactors: CCND2 CDKN2B COPB1 ERBB2 FGFR4 GPR37 GRM1 IGF1R IKBKG KAT2A KDELR2 NEDD4 NF2 PDGFRA TRARG1
GO Annotations	Cellular Component	Plasma Membrane Membrane Chloride Channel Complex
	Molecular Function	Volume-sensitive Anion Channel Activity Intracellularly Calcium-gated Chloride Channel Activity Chloride Channel Activity Calcium Ion Binding Protein Binding Metal Ion Binding Volume-sensitive Chloride Channel Activity
	Biological Process	Monoatomic Ion Transport Chloride Transport L-glutamate Transmembrane Transport Monoatomic Ion Transmembrane Transport Chloride Transmembrane Transport
Pathways	Stimuli-sensing channels
GWAS	Systolic blood pressure (cigarette smoking interaction) ( 26752167 )
Entrez ID	94015
HPRD ID	16394
Ensembl ID	ENSG00000141540
Uniprot IDs	B4DKD1 Q9BSA4
PDB IDs	7P54 7P5M
GO Terms Enriched among Interactors ?	Transmembrane Receptor Protein Tyrosine Kinase Activity Peptidyl-tyrosine Phosphorylation Receptor Complex Regulation Of MAPK Cascade Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of MAPK Cascade Positive Regulation Of Cell Communication Positive Regulation Of Signaling Protein Tyrosine Kinase Activity Regulation Of Intracellular Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Regulation Of Signal Transduction COPI-coated Vesicle Membrane Transport Vesicle Ubiquitin Ligase Complex Protein Autophosphorylation Enzyme-linked Receptor Protein Signaling Pathway Protein Phosphorylation Regulation Of Cell Population Proliferation Phosphorylation Long-term Memory Neuromuscular Junction Development Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Cell Population Proliferation Cell Surface Receptor Signaling Pathway Signal Transduction Protein Kinase Activity Peptidyl-lysine Glutarylation Histone Glutaryltransferase Activity Histone Succinyltransferase Activity Peptide Glutaryltransferase Activity G Protein-coupled Receptor Homodimeric Complex G Protein-coupled Neurotransmitter Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Formation Of Structure Involved In A Symbiotic Process Platelet-derived Growth Factor Alpha-receptor Activity Plasma Membrane Protein Modification Process ERBB3:ERBB2 Complex Kinase Activity Histone H3K9 Acetyltransferase Activity Prosaposin Receptor Activity Dendriole Neurotransmitter Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration G Protein-coupled Receptor Dimeric Complex Channel Inhibitor Activity Odontogenesis Of Dentin-containing Tooth Platelet-derived Growth Factor Receptor-alpha Signaling Pathway