SHKBP1

Description		SH3KBP1 binding protein 1
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GO Annotations	Cellular Component	Lysosome
	Molecular Function	Protein Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Protein Homooligomerization
Pathways		CDC42 GTPase cycle
Drugs
Diseases
GWAS		Carotid intima media thickness (mean) ( 31801372) Cleft lip with or without cleft palate x maternal periconceptional smoking interaction (parent of origin effect) ( 31372216) Hemoglobin levels ( 32327693)
Interacting Genes		14 interacting genes: CCNG1 COL7A1 CUL3 GRB2 HSP90AA1 HSP90AB1 LXN NR3C1 PIN1 PRPF3 SH3KBP1 UBC WEE2-AS1 YWHAG
Entrez ID		92799
HPRD ID		15338
Ensembl ID		ENSG00000160410
Uniprot IDs		Q8TBC3
PDB IDs		4CRH
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Modification Process Regulation Of Protein Stability Ubiquitin Protein Ligase Binding Tau Protein Binding Telomerase Holoenzyme Complex Assembly Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding Protein-RNA Complex Assembly Protein Stabilization RNA Binding Chaperone-mediated Protein Complex Assembly Telomere Maintenance Via Telomerase DNA Polymerase Binding Axonal Growth Cone RNA-templated DNA Biosynthetic Process MHC Class II Protein Complex Binding Disordered Domain Specific Binding Identical Protein Binding Response To Temperature Stimulus Telomere Maintenance Via Telomere Lengthening Protein-containing Complex Assembly Protein Folding Chaperone Complex COP9 Signalosome Regulation Of Biological Quality ATP-dependent Protein Folding Chaperone Endodermal Cell Differentiation Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Protein Ubiquitination Positive Regulation Of Nitric Oxide Metabolic Process Protein-containing Complex Organization Supramolecular Fiber Organization Regulation Of Protein Metabolic Process Collagen Type VII Trimer Guanyl-nucleotide Exchange Factor Adaptor Activity Nuclear Glucocorticoid Receptor Activity CTP Binding DATP Binding Cellular Response To Heat Cis-trans Isomerase Activity Cellular Response To Stress Regulation Of Post-translational Protein Modification Protein Folding Chaperone Nucleoplasm Response To Stress Response To Hormone Regulation Of Nitric Oxide Metabolic Process Regulation Of Nitric Oxide Biosynthetic Process Cellular Response To Amino Acid Starvation Response To Amino Acid Starvation
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