CD8B

Description		CD8 subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Cell Surface Membrane Early Endosome Membrane T Cell Receptor Complex Receptor Complex
	Molecular Function	Protein Binding Coreceptor Activity MHC Class I Protein Binding
	Biological Process	Adaptive Immune Response Immune System Process Immune Response Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway T Cell Activation Regulation Of Immune Response T Cell Receptor Signaling Pathway
Pathways		Nef Mediated CD8 Down-regulation Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Progressive supranuclear palsy ( 21685912)
Novel Interacting Genes		1 novel interacting genes: MRPS5
Interacting Genes		3 interacting genes: CD3D CD8A ST3GAL4
Entrez ID		926
HPRD ID		01725
Ensembl ID		ENSG00000172116
Uniprot IDs		P10966 Q53QL8
PDB IDs
Enriched GO Terms of Interacting Partners?		T Cell Receptor Complex T Cell Receptor Signaling Pathway Cytotoxic T Cell Differentiation Antigen Receptor-mediated Signaling Pathway Beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide Alpha-2,3- Sialyltransferase N-acetyllactosaminide Alpha-2,3-sialyltransferase Activity Adaptive Immune Response Alpha-beta T Cell Receptor Complex Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway T Cell Activation MHC Class I Protein Complex Binding Beta-galactoside (CMP) Alpha-2,3-sialyltransferase Activity Positive T Cell Selection Positive Thymic T Cell Selection Immune Response-activating Signaling Pathway Immune Response-regulating Signaling Pathway External Side Of Plasma Membrane Activation Of Immune Response Regulation Of Immune System Process Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Leukocyte Tethering Or Rolling Sialylation Keratan Sulfate Proteoglycan Biosynthetic Process Keratan Sulfate Proteoglycan Metabolic Process Lymphocyte Activation MHC Class I Protein Binding Sialyltransferase Activity Thymic T Cell Selection Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Oligosaccharide Biosynthetic Process Leukocyte Activation Positive Regulation Of Blood Coagulation T Cell Selection Viral Protein Processing Mitochondrial Small Ribosomal Subunit Positive Regulation Of Coagulation Positive Regulation Of Immune Response Cell Activation Plasma Membrane Raft T Cell Mediated Immunity Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of Cellular Extravasation Protein O-linked Glycosylation Via N-acetyl-galactosamine Oligosaccharide Metabolic Process Coreceptor Activity Proteoglycan Biosynthetic Process Glycolipid Biosynthetic Process Golgi Cisterna Membrane Positive Regulation Of Wound Healing
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